Colorectal cancer in inflammatory bowel diseases: CT features with pathological correlation

Abstract

Colorectal cancer in IBD displays two main features on CT. Type 2 tumors and free-fluid effusion correlate with presence of signet ring cells. Knowledge of these findings is critical to help suggest the diagnosis.

Gastrointestinal cancers in inflammatory bowel disease: An update with emphasis on imaging findings

“…In addition, the application of CT using carbon dioxide (i.e., virtual colonoscopy or CT colonography) has not been recommended in IBD patients (Spada et al, 2015;Gandon, 2014). On CT imaging, IBD-related colon cancers often display the same characteristics than those of sporadic colorectal cancers (Delabrousse et al, 2013;Soyer et al, 2012a;Hristova et al, 2013). They may present as a soft tissue mass that narrows the colonic lumen diplaying the classical "apple core sign".…”

“…They can also appear as a focal and asymmetric colonic wall thickening (Barral et al, 2014;Soyer et al, 2012a;Hristova et al, 2013). Local extension of tumor appears as an extracolic mass or as thickening and infiltration of pericolic fat (Soyer et al, 2012a;Hristova et al, 2013). However, these neoplasms are frequently squirrhous, flat and superimposed on a colon that contains chronically inflamed, thickened and inflamed mucosa (Hristova et al, 2013).…”

“…They may present as a soft tissue mass that narrows the colonic lumen diplaying the classical "apple core sign". They can also appear as a focal and asymmetric colonic wall thickening (Barral et al, 2014;Soyer et al, 2012a;Hristova et al, 2013). Local extension of tumor appears as an extracolic mass or as thickening and infiltration of pericolic fat (Soyer et al, 2012a;Hristova et al, 2013).…”

Extra-intestinal malignancies in inflammatory bowel diseases: An update with emphasis on MDCT and MR imaging features

“…Multidetector row computed tomography (MDCT) and magnetic resonance (MR) imaging are now screening modalities of major importance for diagnosing complications in IBD patients as well as problem-solving tools for IBD patients presenting with unusual symptoms [2][3][4]8]. Consequently, radiologists are currently on the frontline of management of IBD patients in many occasions.…”

“…Gastrointestinal cancers are of major concern in the followup of IBD patients, so that they have already received a great attention in the gastroenterological and radiological literatures [4][5][6][7][8][9]. However, although they are somewhat rarer, extra-intestinal malignancies associated with IBD, such as cholangiocarcinoma, lymphoma and skin cancers may occur and the risk is increased by immunosuppressive treatments [10][11][12][13][14][15][16][17][18][19][20].…”