Colonic motor activity and bowel function. I. Normal movement of contents.

Ritchie, James

doi:10.1136/gut.9.4.442

Cited by 106 publications

(49 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This is seen to be in agreement with G. IT HAS been shown repeatedly that the formation of platelet plugs in vivo requires a minimum of flow [1]. The influence of the flow regime on the coagulation time, the morphology and consistency of the blood coagulum have been studied extensively by DINTENFASS [2]. Direct microscopic observation showed that the acceleration of coagulation in whole blood at high shear rates was accompanied by shear dependent platelet aggregation [3].…”

Section: Rheo-stimulation a New Methods And Its Application In The Assupporting

confidence: 78%

“…BASED on our work on peristalsis [1] in the upper urinary tract, we are presently studying some biorheological aspects of the motility of the large intestine (colon). The large intestine is capable of a variety of movements described and classified in the medical literature [2]. In order to carry out an analysis for the intraluminal pressure and velocity fields associated with such movements, the rheological properties of the colonic contents (chyme) were needed.…”

Section: Rheo-stimulation a New Methods And Its Application In The Asmentioning

confidence: 99%

“…(1) ellipsoid deformation and orientation of cells in flow, major axis parallel to flow direction [2,4]; (2) tank tread like rotation of red cell membrane around the cell content [2,4] and migration of red cells along shear stress gradients; (3) relative apparent blood viscosity inversely related to plasma viscosity [2 and many other authors]; (4) fluidity of packed cells [1, 2 and others].…”

Section: Correlations Between Micro-and Macro-circulatory Changes Durmentioning

confidence: 99%

See 2 more Smart Citations

II. Free Communications

1972

BIR

View full text Add to dashboard Cite

By MEANS of a universal tensile testing instrument, stress-strain relationships were studied on longitudinal and circumferential strips excised from various portions of the caval vein and from the cervical, axillary, iliac and femoral veins of dogs. In order to investigate the mechanical properties from the architectural point of view, the relationships were also studied on the nuchal ligament, tendon and intestinal smooth muscle bundle which are composed mainly of elastin, collagen and smooth muscle fibers, respectively. Histological examinations were also carried out with these vascular and non-vascular specimens.The results obtained were summarized as follows: (1) the circumferential distensibility of the veins in low stress range is determined mainly by mechanical characteristics of smooth muscle fibers; (2) the circumferential distensibility of the veins approaches the distensibility of collagen fibers asymptotically in high stress range; (3) SINCE the classic study of WHITTAKER and WINTON (1933) on the canine hindlimb, the discrepancy between blood viscosity measured in isolated tissue and laboratory viscometers has been attributed to the FahraeusLindqvist effect. In the present study, Whittaker and Winton's experiments were repeated with the use of freshly isolated limbs and both red cell suspensions and cell-free plasma expanders as perfusates. In addition, limbs fixed in formaldehyde were perfused with Newtonian plasma expanders of known viscosity. In both sets of experiments large discrepancies were consistently found in values of in vivo viscosity for the various cell-free perfusates, an anomaly that cannot be explained on the basis of a Fahraeus-Lindqvist effect. A likely explanation for the differences between in vivo and in vitro viscosity in the present experiments and in those of previous workers is the occurrence of nonlinear inertial pressure losses.

show abstract

Section: Rheo-stimulation a New Methods And Its Application In The Assupporting

confidence: 78%

Section: Rheo-stimulation a New Methods And Its Application In The Asmentioning

confidence: 99%

Section: Correlations Between Micro-and Macro-circulatory Changes Durmentioning

confidence: 99%

See 1 more Smart Citation

II. Free Communications

1972

BIR

View full text Add to dashboard Cite

show abstract

“…In spite of the total number of neurons being smaller, there is evidence that the incidence of muscle contractions is greater in the descending colon 5 , which could explain the greater proportion of metabolically active neurons in this organ. The fact that we did not encounter differences in this subpopulation in the intestinal circumference, as well as in the general neuronal population, allow us to suggest that the fecal propulsion in the descending colon is made in a circularly uniform way, as evidenced by fluoroscopy in the descending colon of humans 4 .…”

Section: Discussionmentioning

confidence: 65%

“…In the ascending colon the feces are temporarily stored, favoring the absorption of the excess fluid [1][2][3] . The descending colon, on the other hand, expels the fecal matter and exhibits a pattern of intense peristaltic movements, controlled trough reflexes triggered by the action of the dehydrated faces [2][3][4][5] , so that it stores them for a short period 1,2 . The colonic activities are coordinated mainly by the nervous system and modulated by secretions such as hormones, bacterial enterotoxins, long-chain fatty acids, and endogenous stimulants 1 .…”

mentioning

confidence: 99%

Regional differences in the number and type of myenteric neurons in the descending colon of rats

Araújo

Sant’Ana

Molinari

et al. 2003

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

-The purpose of this study was to analyze the neuronal density of the myenteric plexus of the intermediate and antimesocolic regions of the descending colon of rats. Whole-mounts were stained with three different techniques of neuronal evidenciation. Through counts of the number of neurons in an area of 6.64 mm 2 under light microscopy, we found 1,271 ± 227.54 neurons with Giemsa in the intermediate region and 1,234 ± 225.92 neurons in the antimesocolic region; with the NADH-diaphorase technique we found 530 ± 92.97 neurons in the intermediate region and 539 ± 146.72 neurons in the antimesocolic region; and through the NADPH-diaphorase histochemistry, we found 417 ± 34.42 neurons in the intermediate region and 547 ± 84.01 neurons in the antimesocolic region. We conclude that there is a variation in the density of NADPH-diaphorase positive neurons in the intestinal circumference; that the NADH-diaphorase positive neuronal subpopulation represented 42.7% of that stained with Giemsa; and that the NADPH-diaphorase positive neurons represented 37.8% of the whole myenteric population.KEY WORDS: myenteric plexus, Giemsa, NADH-diaphorase, NADPH-diaphorase, rat, descending colon.Diferenças regionais no número e tipo de neurônios mioentéricos do colo descendente de ratos Diferenças regionais no número e tipo de neurônios mioentéricos do colo descendente de ratos Diferenças regionais no número e tipo de neurônios mioentéricos do colo descendente de ratos Diferenças regionais no número e tipo de neurônios mioentéricos do colo descendente de ratos Diferenças regionais no número e tipo de neurônios mioentéricos do colo descendente de ratos RESUMO -O objetivo deste estudo foi analisar a densidade neuronal do plexo mioentérico das regiões intermediária e antimesocólica do colo descendente de ratos. Preparados de membrana foram corados com três técnicas diferentes de evidenciação neuronal. Através da contagem do número de neurônios, em uma área de 6,64 mm 2 , sob microscopia de luz, encontramos com a coloração de Giemsa: 1271 ± 227,54 neurônios na região intermediária e 1234 ± 225,92 na região antimesocólica. Utilizando a técnica de marcação da NADH-diaforase, encontramos 530 ± 92,97 neurônios na região intermediária e 539 ± 146,72 na região antimesocólica. Através da histoquímica da NADPH-diaforase, encontramos 417 ± 34,42 neurônios na região intermediária e 547 ± 84,01 na região antimesocólica. Concluímos que há uma variação da densidade de neurônios NADPH-diaforase positivos ao redor da circunferência intestinal; que a subpopulação neuronal NADH-diaforase positivos representou 42,7% da população evidenciada no Giemsa e que os neurônios NADPHdiaforase positivos representam 37,8% do total. PALAVRAS-CHAVE: plexo mioentérico, Giemsa, NADH-diaforase, NADPH-diaforase, rato, colo descendente.

show abstract

Colonic Motility in the Irritable Bowel Syndrome

Burns¹

1980

Arch Intern Med

View full text Add to dashboard Cite

Colonic motor activity and bowel function. I. Normal movement of contents.

Cited by 106 publications

References 11 publications

II. Free Communications

II. Free Communications

Regional differences in the number and type of myenteric neurons in the descending colon of rats

Colonic Motility in the Irritable Bowel Syndrome

Contact Info

Product

Resources

About