Colobomata of the Optic Nerve Sheath in Rats

Comparison of the Lamina Cribrosa in Mammalian Species With Good and With Indifferent Vision

“…3). Similar colobomata, also associated with no sign of a lamina cribrosa, have already been reported in the rat (Nicholls and Tansley, 1938 Investigation of other laboratory mammals revealed that the rabbit also has no collagen at the site of entry of the optic nerve into the eye. Associated with this condition there was an almost universal cupping of the optic disc, more or less severe (Fig.…”

Degenerations of the Dog Retina : II. Generalized Progressive Atrophy of Hereditary Origin

“…Although Nicholls (1938) reproduced these results; he found that some two-thirds of the posterior ciliary arteries had to be tied off before degeneration occurred, and that this degeneration affected rods and cones similarly as regards rate and extent. He concluded that the necessary interference with the blood supply was so extensive that a similar interference was unlikely to be the cause of spontaneous retinal degeneration in man.…”

Degenerations of the Dog Retina : I. Structure and Development of the Retina of the Normal Dog

“…(c) Occasional Anomalies.-We have observed colobomata adjacent to the optic papilla as described by Nicholls and Tansley (1938), and Blessig-Henle cavities in the extreme peripheral 500 of the non-tapetal fundus as described by Zurn (1902). The incidence of each anomaly was about I *5 per cent of the eyes examined histologically.…”