“…We selected only patients with high pretest probability of CD (suggestive symptoms, risk factors, comorbid conditions) and with positivity of anti‐TTG antibodies and EMA. Some clinical conditions, such as liver disease, rheumatoid arthritis, and inflammatory bowel disease, can cause a falsely positive anti‐TTG result (30,31), but when both anti‐TTG and EMA are positive in a patient with suggestive symptoms and/or risk factors, the probability that the patient had CD is extremely high, almost 100% (7). Furthermore, most Italian laboratories use the diagnostic protocol proposed by the Autoimmunity and Allergology Study Group of the Italian Society of Laboratory Medicine, which provides an initial screening with a highly sensitive test (anti‐TTG) confirmed, if positive, by EMA (32).…”