Collagenous colitis in adult Sri Lankans: experience from the Indian subcontinent

Satarasinghe, Ravindra

doi:10.1136/gut.2005.084681

Cited by 7 publications

(2 citation statements)

References 2 publications

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“…Calprotectin is 36 kDa calcium- and zinc-binding protein that represents 60% of cytosolic proteins in granulocytes. 19 It is stable in feces when stored at room temperature for up to 1 week. 20 The concentration of calprotectin in feces is an indirect measure of neutrophil infiltrate in the bowel mucosa.…”

Section: Tests Used To Evaluate Patients With Symptoms Of Ibdmentioning

confidence: 99%

The Utility of Biomarkers in the Diagnosis and Therapy of Inflammatory Bowel Disease

2011

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Fecal and serologic biomarkers can be used in the diagnosis and management of inflammatory bowel disease (IBD). Fecal markers such as calprotectin and lactoferrin have been studied for their ability to identify patients with IBD, assess disease activity, and predict relapse. Antibodies against Saccharomyces cerevisiae and perinuclear antineutrophil cytoplasmic proteins have been used in diagnosis of IBD, to distinguish Crohn's disease (CD) from ulcerative colitis, and to predict the risk of complications of CD. Tests for c-reactive protein and erythrocyte sedimentation rate have been used to assess inflammatory processes and predict the course of IBD progression. Levels of drug metabolites and antibodies against therapeutic agents might be measured to determine why patients do not respond to therapy and to select alternative treatments. This review addresses the potential for biomarker assays to improve treatment strategies and challenges to their use and development.

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Section: Tests Used To Evaluate Patients With Symptoms Of Ibdmentioning

confidence: 99%

The Utility of Biomarkers in the Diagnosis and Therapy of Inflammatory Bowel Disease

2011

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“…However, it must be noted that cases of MC have been reported in practically all parts of the world. On considering only those studies with a sample size of ≥150 patients, the mean frequency of MC is seen to be 12.1 ± 6.2% (range 3.7–29.3%) (Table S5). Some studies have evaluated the frequency of MC with respect to patient age.…”

Section: Statements and Recommendationsmentioning

confidence: 99%

Current concepts on microscopic colitis: evidence‐based statements and recommendations of the Spanish Microscopic Colitis Group

Fernández‐Bañares

Casanova

Arguedas

et al. 2015

Aliment Pharmacol Ther

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Summary Background Microscopic colitis (MC) is an underdiagnosed inflammatory bowel disease. Aim To develop an evidence‐based clinical practice guide on MC current concepts. Methods Literature search was done on the Cochrane Library, EMBASE and MEDLINE electronic databases, which were consulted covering the period up until March 2015. Work groups were selected for each of the reviewed topics, with the purpose of drafting the initial statements and recommendations. They subsequently underwent a voting process based on the Delphi method. Each statement/recommendation was accompanied by the result of the vote the level of evidence, and discussion of the corresponding evidence. The grade of recommendation (GR) using the GRADE approach was established for diagnosis and treatment recommendations. Results Some key statements and recommendations are: advancing age increases the risk of developing MC, mainly in females. The symptoms of MC and IBS‐D may be similar. If MC is suspected, colonoscopy taking biopsies is mandatory. Treatment with oral budesonide is recommended to induce clinical remission in patients with MC. Oral mesalazine is not recommended in patients with collagenous colitis for the induction of clinical remission. The use of anti‐TNF‐alpha drugs (infliximab, adalimumab) is recommended for the induction of remission in severe cases of MC that fail to respond to corticosteroids or immunomodulators, as an alternative to colectomy. Conclusions This is the first consensus paper on MC based on GRADE methodology. This initiative may help physicians involved in care of these patients in taking decisions based on evidence.

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Advances for improved diagnosis of microscopic colitis in patients with chronic diarrhoea

Zabana

Ferrer

Aceituno

et al. 2017

Gastroenterología y Hepatología (English Edition)

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Collagenous colitis in adult Sri Lankans: experience from the Indian subcontinent

Cited by 7 publications

References 2 publications

The Utility of Biomarkers in the Diagnosis and Therapy of Inflammatory Bowel Disease

The Utility of Biomarkers in the Diagnosis and Therapy of Inflammatory Bowel Disease

Current concepts on microscopic colitis: evidence‐based statements and recommendations of the Spanish Microscopic Colitis Group

Advances for improved diagnosis of microscopic colitis in patients with chronic diarrhoea

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