Collagen and Elastic Content of Abdominal Skin After Surgical Weight Loss

Orpheu, Simone Cristina; Coltro, Pedro Soler; Scopel, Gean Paulo; Gómez, David S.; Rodrigues, Consuelo Junqueira; Modolin, Miguel; Faintuch, Joel; Gemperli, Rolf; Ferreira, Marcos Castro

doi:10.1007/s11695-009-0019-0

Cited by 51 publications

(43 citation statements)

References 20 publications

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“…Another study reported that obese mice demonstrate poor wound collagen deposition, which might be due to adipose tissue structural changes [32,35]. A more recent study by Orpheu et al reported that postbariatric patients had a limited collagen network, although elastic fiber content was the similar in obese and non-obese patients [36]. However, there are also reports demonstrating obesity does not alter skin quality [37], but the process of MWL itself creates damage in the extracellular matrix [38].…”

Section: Discussionmentioning

confidence: 99%

Biomechanical Properties of Skin in Massive Weight Loss Patients

et al. 2010

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Section: Discussionmentioning

confidence: 99%

Biomechanical Properties of Skin in Massive Weight Loss Patients

et al. 2010

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“…In a previous study we documented depletion of collagen, but not of elastic fibers, in the dermis of female bariatric candidates, contributing to the lax skin [7]. Redundant skin folds impair selfstem.…”

Section: Discussionmentioning

confidence: 78%

Quality of Life after Postbariatric Abdominoplasty in Females: Interest of Age, Current Weight and Weight Loss

W¹

2015

J Obes Weight Loss Ther

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Background: Aiming to analyze whether abdominoplasty might benefit quality of life of postbariatric females with redundant abdominal skin folds beyond the first year, a clinical investigation after 2-4 years was designed. Despite being a reputed and popular procedure after massive weight loss, results are still debated. It was hypothesized that sustained improvements in quality of life, independent of previous anti-obesity gastroplasty, would be demonstrated.

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“…They also depend on the level of physical activity, lack of use, nutrition status, denervation, and chronic physiological stress. In this field of research, morphological and histochemical methods of analysis have been useful in the study of muscle anatomy and physiology 12 . Although a large number of collagen types have been identified, the exact role of their structural functions in the different tissues of the body, especially in muscles, is still not well established.…”

Section: Discussionmentioning

confidence: 99%

Immunohistochemical analysis of collagen content and types in the rectus abdominis muscle of cadavers of different ages

et al. 2011

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PURPOSE:To assess the collagen content and types in the rectus abdominis muscle of cadavers of different ages. METHODS: Forty fresh adult male cadavers, at room temperature, were obtained from the Institute of Legal Medicine of Franca and dissected within 24 hours of death. The cadavers were divided into two groups: Group A (n=20), 18 to 30 years of age, and Group B (n=20), 31 to 60 years of age. Bilateral incisions were made in the middle portion of anterior rectus sheath 3 cm superiorly and 2 cm inferiorly to the umbilicus and four fragments of the rectus abdominis muscle were dissected. The samples were fixed in 10% buffered formalin and sent for immunohistochemical analysis to determine collagen content and types. RESULTS: Immunohistochemical results revealed higher amounts of type I and type III collagen in Group A. However, no difference in the amount of type IV collagen was found between the groups. CONCLUSION: The amount of type I and type III collagen was higher in group A. Key words: Collagen. Rectus Abdominis. Age Groups. Cadaver. RESUMO OBJETIVO:Avaliar o colágeno no músculo reto do abdome em cadáveres de diferentes faixas etárias. MÉTODOS: Foram dissecados 40 cadáveres adultos masculinos, não fixados, com tempo de óbito de até 24 horas, em temperatura ambiente, provenientes do Instituto Médico-Legal de Franca (SP -Brasil). Os cadáveres foram distribuídos em dois grupos: GRUPO A (n=20) -18 a 30 anos e GRUPO B (n=20) -31 a 60 anos. Realizou-se incisão na porção mediana da lâmina anterior da bainha do músculo reto a 3 cm superiormente e 2 cm inferiormente ao umbigo em ambos os lados, sendo retirados quatro fragmentos de músculo reto do abdome. Esse material foi conservado em formalina tamponado a 10% e enviado para imuno-histoquímica para determinação do tipo de colágeno. RESULTADOS: Na Imunihistoquímica os colágenos I e III foram estatisticamente maiores no grupo A, porém não houve diferença entre os grupos em relação ao colágeno IV. CONCLUSÃO: A quantidade de colágeno tipo I e III foi maior no grupo A. Descritores: Colágeno. Reto do Abdome. Grupos Etários. Cadáver.

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Collagen and Elastic Content of Abdominal Skin After Surgical Weight Loss

Cited by 51 publications

References 20 publications

Biomechanical Properties of Skin in Massive Weight Loss Patients

Biomechanical Properties of Skin in Massive Weight Loss Patients

Quality of Life after Postbariatric Abdominoplasty in Females: Interest of Age, Current Weight and Weight Loss

Immunohistochemical analysis of collagen content and types in the rectus abdominis muscle of cadavers of different ages

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