Cold and Cough Medications for Children: Dangerous and Over the Counter!

Yust, E.; Slattery, Ann P.

doi:10.1016/j.cpem.2012.09.007

Cited by 6 publications

(2 citation statements)

References 36 publications

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“…Neurological and cardiovascular adverse events including death have been repeatedly reported in the pediatric literature with therapeutic and supratherapeutic doses of over-the-counter cough and cold medications [ 11 ]. However, few cases were reported in adults.…”

Section: Discussionmentioning

confidence: 99%

Seizures provoked by over-the-counter cough and cold medications in an elderly patient: a case report

2023

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Background Seizures are common neurological emergencies in the elderly that are frequently provoked. Geriatrics have higher rates of neurological disorders and other comorbidities that could affect seizure threshold. Case presentation An 83-year-old male Arabic patient presented to the emergency department with an acute confusional state and urinary incontinence followed by a witnessed tonic–clonic seizure in the hospital. Thorough investigations and imaging were positive only for nonspecific magnetic resonant imaging findings with a negative electroencephalogram. The patient was diagnosed with provoked seizure due to over-the-counter cold medications that included pseudoephedrine and caffeine. He was not prescribed antiepileptic medications at discharge and did not develop subsequent seizures up to this date. Conclusion Over-the-counter cough and cold medications with sympathomimetic ingredients can be associated with provoked seizures in the elderly. Physicians should be aware of the potentially serious adverse events associated with commonly used nonprescription sympathomimetics such as pseudoephedrine and caffeine in elderly patients.

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Section: Discussionmentioning

confidence: 99%

Seizures provoked by over-the-counter cough and cold medications in an elderly patient: a case report

2023

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“…Children generally recieve OTC medication at home to treat fever, cough, upper respiratory tract infections and pain (Martín-Pérez et al, 2014;Trajanovska et al, 2010). Inappropriate using of OTC medication at home such as cold and cough product have emerged an important public health issue due to drug safety and efficacy (Hampton et al, 2013;Yust & Slattery, 2012). Mothers' administration of OTC medication to children at home lead to occur serious side effects in children (Martín-Pérez et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Examination of Mothers' Over-The-Counter-Medication (OTC) Usage at Home According to Different Socioeconomic and Health Literacy Levels

Ay¹,

Boztepe²

2021

Balıkesır Health Sciences Journal

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Objective:The purpose of this study was to examine mothers' OTC medication usage at home according to different socioeconomic and health literacy levels and the effecting factors. Materials and Methods: This cross-sectional descriptive study was carried out in three family health centers from different socioeconomic levels (low-middle-high) between September 2018 and February 2019. The sample of the study consisted of 300 mothers of 0-18-year-old children who met the research criteria. Data were collected through "Data Collection Form" and "Adult Health Literacy Scale". Results: It was determined that mothers in low socioeconomic group had high level of OTC medication usage to their children at home. A significant relationship was found between the mean scores of mothers' health literacy and socioeconomic level (p<0.000). The mean scores of mothers' health literacy in low socioeconomic group who used OTC medication to their children at home are lower than mothers who did not use OTC medication (p: 0.041). It was determined that child's age (OR=1.01, p=0.045), regular medication usage in mother (OR=2.11, p=0.014) and reading the prospectus before giving medication to their child (OR=3.14, p=0.005) effected to mothers' OTC medication usage at home. Conclusion: This study emphasized that low socioeconomic and health literacy levels may cause mothers' OTC medication usage to their children at home. OTC medication usage can be decreased with education programs that take into account the effecting factors to mothers' OTC medication usage and aim to increase health literacy levels.

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Antihistamines prescribed off-label among paediatric patients at a tertiary care hospital setting in Malaysia

Tan

Shah

2016

Int J Clin Pharm

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Background Antihistamines are widely prescribed to children but should be used with caution in young children. Objective To determine the paediatric prescribing pattern of antihistamines with a focus on the off-label prescribing and factors that influence such prescribing. Setting Paediatric wards of a tertiary care hospital setting in Malaysia. Methods The pharmacy-based computer system and medical records were used to collect the required data. Labelling status of each antihistamine was determined based on the information provided in the product leaflets. Main outcome measure Antihistamines prescribed off-label and factors associated with such prescribing. Results Of the 176 hospitalised children aged <18 years prescribed with an antihistamine in the year 2012, 60.8 % received it in an off-label manner. Of 292 antihistamine prescription items, 55.5 % were prescribed off-label. Loratadine (35.3 %) was the most frequently prescribed antihistamine and chlorpheniramine maleate (34.0 %) was the most common antihistamine prescribed off-label. The main reason for the off-label prescribing of antihistamines was prescribing at higher than the recommended dose (30.2 %). Binary logistic regression showed that children aged <2 years (OR 12.65; 95 % CI 2.87-55.67) and the number of medications received (OR 1.14; 95 % CI 1.00-1.29) were significant predictors for the off-label prescribing of antihistamines. Conclusion Prescribing antihistamines for children in an off-label manner was prevalent at the studied locations and warrants further investigation on the consequences of such prescribing.

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Cold and Cough Medications for Children: Dangerous and Over the Counter!

Cited by 6 publications

References 36 publications

Seizures provoked by over-the-counter cough and cold medications in an elderly patient: a case report

Seizures provoked by over-the-counter cough and cold medications in an elderly patient: a case report

Examination of Mothers' Over-The-Counter-Medication (OTC) Usage at Home According to Different Socioeconomic and Health Literacy Levels

Antihistamines prescribed off-label among paediatric patients at a tertiary care hospital setting in Malaysia

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