Cold-Adapted Fungi as a Source for Valuable Metabolites

Frisvad, Jens Christian

doi:10.1007/978-3-540-74335-4_22

Cited by 9 publications

(4 citation statements)

References 67 publications

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“…Marine extremophilic microorganisms, including fungi, can also represent a huge reservoir of bioactive molecules that have recently triggered interest in bioprospecting research because of their promising therapeutical properties [ 21 , 22 , 29 , 109 , 152 , 155 , 156 , 157 , 158 , 159 ]. In this regard, marine fungi isolated from polar environments reported their ability to synthesize metabolites with unique structures and a wide range of biological activities, compared to mesophilic fungi, highlighting that psychrophilic fungi can be a new resource for several applications in biotechnology [ 28 , 30 , 160 , 161 , 162 ]. However, the search for natural bioactive products has been focused so far on a very small number of fungi isolated from Antarctic marine sediments, seawater and few organisms such as sponges and macroalgae [ 27 ].…”

Section: Biotechnological Potential Of Fungi Inhabiting Marine Antarctic Environmentsmentioning

confidence: 99%

Diversity, Ecological Role and Biotechnological Potential of Antarctic Marine Fungi

Varrella

Barone

Tangherlini

et al. 2021

JoF

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The Antarctic Ocean is one of the most remote and inaccessible environments on our planet and hosts potentially high biodiversity, being largely unexplored and undescribed. Fungi have key functions and unique physiological and morphological adaptations even in extreme conditions, from shallow habitats to deep-sea sediments. Here, we summarized information on diversity, the ecological role, and biotechnological potential of marine fungi in the coldest biome on Earth. This review also discloses the importance of boosting research on Antarctic fungi as hidden treasures of biodiversity and bioactive molecules to better understand their role in marine ecosystem functioning and their applications in different biotechnological fields.

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Section: Biotechnological Potential Of Fungi Inhabiting Marine Antarctic Environmentsmentioning

confidence: 99%

Diversity, Ecological Role and Biotechnological Potential of Antarctic Marine Fungi

Varrella

Barone

Tangherlini

et al. 2021

JoF

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“…Arctic fungi find applications in the field of biotechnology because they produce substances such as enzymes, polyunsaturated fatty acids, antifreeze proteins, and secondary metabolites (Feller and Gerday, 2003;Hoshino et al, 2003;Frisvad et al, 2006;Frisvad, 2008;Leary, 2008). As decomposers, these fungi also form an important part of the nutrient cycle (Ludley and Robinson, 2008).…”

Section: Introductionmentioning

confidence: 99%

Filamentous Soil Fungi from Ny-Ålesund, Spitsbergen, and Screening for Extracellular Enzymes

Singh¹,

Singh²,

Yadav³

et al. 2012

ARCTIC

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“…Similarly, biochemical adaptations allow macromycete species to survive extreme environmental factors that include low temperatures, intermittent freezing and relatively high exposure to ultraviolet rays (Jang et al 2000;Feller & Gerday 2003;Hoshino et al 2003). These adaptations may provide compounds, such as cold tolerant enzymes and antimicrobial compounds (Fiedurek et al 2003;Frisvad 2008), with biotechnological potential (Leary 2008). There is therefore a need to screen Arctic mushrooms for biotechnological prospecting.…”

mentioning

confidence: 99%

Chemical constituents and antioxidant activity of the Arctic mushroomLycoperdon mollePers

Singh¹,

Singh²,

D’Souza³

et al. 2012

Polar Research

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The biochemical adaptations of fungi to the harsh conditions of the Arctic may mean that these organisms have properties useful to people. Using samples of the puffball mushroom Lycoperdon molle Pers. (Basidiomycota, Fungi) collected at Ny-Ålesund, Svalbard, we examined the in vitro antioxidant potential of this species by investigating its free-radical scavenging (FRS) activity, inhibition of lipid peroxidation (ILP) and Trolox equivalent antioxidant capacity (TEAC). The FRS activity of the samples in various organic solvents, including methanol, ethanol, acetone and dimethyl sulfoxide (DMSO), were found to be in the range of 44.00–89.60%, while ILP activities ranged from 32.00 to 54.41%. The methanol extract showed the highest levels of FRS (89.60%) and ILP (54.41%) compared to standard antioxidants butylated hydroxyanisol and butylated hydroxytoluene (BHT). The TEAC value was also found to be higher compared to the standard water soluble vitamin E analogue Trolox (3.9 mM). Antimicrobial screening of Lycoperdon molle extracts was negative to the tested microorganisms. Using electrospray ionization mass spectrometry (ESI-MS), we determined that the samples contained compounds such as phosphoethanolamine, monomethyl arsenic acid, phosphatidyl glycerol, phosphoionositol, phosphoserine and lysophosphatidyl choline. We found that Lycoperdon molle showed strong antioxidant abilities compared to the standards, suggesting that this and perhaps other Arctic mushrooms could be valuable sources of natural antioxidants for the pharmaceutical industry. To our knowledge, this is the first report of the antioxidant activity in any Arctic mushroom

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Cold-Adapted Fungi as a Source for Valuable Metabolites

Cited by 9 publications

References 67 publications

Diversity, Ecological Role and Biotechnological Potential of Antarctic Marine Fungi

Diversity, Ecological Role and Biotechnological Potential of Antarctic Marine Fungi

Filamentous Soil Fungi from Ny-Ålesund, Spitsbergen, and Screening for Extracellular Enzymes

Chemical constituents and antioxidant activity of the Arctic mushroomLycoperdon mollePers

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