Coinheritance of generalized pustular psoriasis and familial Behçet‐like autoinflammatory syndrome with variants in <i><scp>IL</scp>36<scp>RN</scp></i> and <i><scp>TNFAIP</scp>3</i> in the heterozygous state

Liang, Jianying; Zhang, Hui; Guo, Yuxin; Yang, Kun; Ni, Cheng; Yu, Hong; Kong, Xianguo; Li, Ming; Lu, Zengjun; Yao, Zhirong

doi:10.1111/1346-8138.15034

Cited by 9 publications

(1 citation statement)

References 15 publications

(44 reference statements)

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“…Psychosomatic and hereditary factors have been suggested to have a role in the etiology of geographic tongue. Liang et al (2019) reported that biopsies revealed similarities among geographic tongue patients with different genotypes with the neutrophils prominently infiltrating the epidermis and the expression ratio of IL‐36Ra/IL‐36γ in lesioned tongues with individuals harboring different genotypes decreased significantly compared with controls.…”

Section: Discussionmentioning

confidence: 99%

Worldwide prevalence of geographic tongue in adults: A systematic review and meta‐analysis

et al. 2022

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To identify the prevalence of geographic tongue in patients >18 years. A systematic literature review was performed in search of population‐based observational studies. Searches were performed using five main databases: Embase, LILACS, PubMed, Scopus and Web of Science; and three gray literature sources: Google Scholar, ProQuest, and OpenGrey. In addition, a manual search in the reference list and consultation with experts on the topic studied were performed. Methodological quality was assessed using the Joanna Briggs Institute's checklist for prevalence studies. Ratio meta‐analyses were performed using JAMOVI. Initially, 3046 studies were identified. After a two‐phase selection, 11 studies were included for quantitative synthesis. Two studies were classified as of low methodological quality, five studies as of moderate quality, and four as of high quality. Two types of prevalence were analyzed: by period and point. Three studies were included in the period prevalence meta‐analysis, and the prevalence was 3% (Confidence interval [CI]: 0.4%–5.5%, n = 9813). Eight studies were included in the point‐prevalence meta‐analysis, and the prevalence was 3% (CI: −0.2% to 5.5%, n = 10,967). Although there are phases of exacerbation and remission in geographic tongue, prevalence and period prevalence were similar. Approximately one in 30 adults has a geographic tongue.

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Section: Discussionmentioning

confidence: 99%

Worldwide prevalence of geographic tongue in adults: A systematic review and meta‐analysis

et al. 2022

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A20 Haploinsufficiency: A Systematic Review of 177 Cases

Elhani,

Riller,

Boursier

et al. 2024

Journal of Investigative Dermatology

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Targeting NF-κB pathway for the therapy of diseases: mechanism and clinical study

Lin

Zhang

et al. 2020

Sig Transduct Target Ther

927

568

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NF-κB pathway consists of canonical and non-canonical pathways. The canonical NF-κB is activated by various stimuli, transducing a quick but transient transcriptional activity, to regulate the expression of various proinflammatory genes and also serve as the critical mediator for inflammatory response. Meanwhile, the activation of the non-canonical NF-κB pathway occurs through a handful of TNF receptor superfamily members. Since the activation of this pathway involves protein synthesis, the kinetics of non-canonical NF-κB activation is slow but persistent, in concordance with its biological functions in the development of immune cell and lymphoid organ, immune homeostasis and immune response. The activation of the canonical and non-canonical NF-κB pathway is tightly controlled, highlighting the vital roles of ubiquitination in these pathways. Emerging studies indicate that dysregulated NF-κB activity causes inflammation-related diseases as well as cancers, and NF-κB has been long proposed as the potential target for therapy of diseases. This review attempts to summarize our current knowledge and updates on the mechanisms of NF-κB pathway regulation and the potential therapeutic application of inhibition of NF-κB signaling in cancer and inflammatory diseases.

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Coinheritance of generalized pustular psoriasis and familial Behçet‐like autoinflammatory syndrome with variants in IL36RN and TNFAIP3 in the heterozygous state

Cited by 9 publications

References 15 publications

Worldwide prevalence of geographic tongue in adults: A systematic review and meta‐analysis

Worldwide prevalence of geographic tongue in adults: A systematic review and meta‐analysis

A20 Haploinsufficiency: A Systematic Review of 177 Cases

Targeting NF-κB pathway for the therapy of diseases: mechanism and clinical study

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