Cohort Profile: The Cork and Kerry Diabetes and Heart Disease Study

Kearney, Patricia M.; Harrington, Janas M.; McCarthy, Vera J. C.; Fitzgerald, Anthony P.; Perry, Ivan J.

doi:10.1093/ije/dys131

Cited by 77 publications

(73 citation statements)

References 19 publications

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“…The problem of increasing obesity and overweight is not unique to Ireland, but is common amongst most developed countries [28,29]. Also, more recent estimates of diabetes prevalence from cohort studies in Ireland are of concern [30]. Furthermore, the decline in CHD mortality rates among those aged over 65 years has notably slowed and compounds the recent Irish study on AMI hospitalization rates [9].…”

Section: Discussionmentioning

confidence: 99%

Modelling Coronary Heart Disease Mortality declines in the Republic of Ireland, 1985–2006

Kabir

Perry

Critchley

et al. 2013

International Journal of Cardiology

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Background: Consistent declines in coronary heart disease (CHD) death rates have been previously observed in Ireland since1985. Aims & Methods: To use the previously validated Irish IMPACT CHD mortality model to further examine the subsequent CHD mortality falls from 1985 through to 2006, and to determine the contribution of risk factor changes and "evidence based" treatments to this decline by age and gender. Results: CHD mortality rates fell by 68% in men (63% in 65-84 years) and by 69% in women (66% in 65-84 years). This resulted in approximately 6450 fewer CHD deaths than if mortality rates had not changed. Overall, approximately 40% (38% in men; 45% in women) of the CHD mortality decline could be attributed to improvements in treatment uptake, particularly secondary prevention (12%), angina (9%), and heart failure therapies (8%). Approximately 48% of the CHD mortality decline was attributable to risk factor improvements (54% in men; 37% in women); the biggest contributions came from falls in population systolic pressure (28%), cholesterol (24%), and physical inactivity levels (10%). Negative trends in diabetes and obesity levels generated an estimated 17% additional CHD deaths. The largest benefits from improvements in risk factors were seen in men aged 25-64 years, while the greatest treatment benefits occurred in women aged 65-84 years. The model explained approximately 88% of the observed mortality declines. Conclusion: Falls in CHD mortality have continued in both sexes in Ireland, but with notable gender and age differences. The continued increase in diabetes and obesity levels is particularly worrying.

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Section: Discussionmentioning

confidence: 99%

Modelling Coronary Heart Disease Mortality declines in the Republic of Ireland, 1985–2006

Kabir

Perry

Critchley

et al. 2013

International Journal of Cardiology

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“…The Cork and Kerry Diabetes and Heart Disease Study (Phase II) was a single centre, cross-sectional study conducted between 2010 and 2011 (Kearney et al, 2013). A population representative random sample was recruited from a large primary care centre in Mitchelstown, County Cork, Ireland (Mitchelstown cohort).…”

Section: Study Design and Subject Recruitmentmentioning

confidence: 99%

Depressive symptoms, anxiety and well-being among metabolic health obese subtypes

Phillips

Perry

2015

Psychoneuroendocrinology

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“…Study methods and protocols have previously been described (33)(34)(35) . All procedures were carried out with reference to the detailed guidelines outlined in the 'Standard Operating Procedures Manual' (36,37) .…”

Section: Study Populationmentioning

confidence: 99%

Capturing changes in dietary patterns among older adults: a latent class analysis of an ageing Irish cohort

Harrington

Dahly

Fitzgerald

et al. 2014

Public Health Nutr.

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Objective: Data-driven approaches to dietary patterns are under-utilized; latent class analyses (LCA) are particularly rare. The present study used an LCA to identify subgroups of people with similar dietary patterns, explore changes in dietary patterns over a 10-year period and relate these dynamics to sociodemographic factors and health outcomes. Design: The 1998 baseline and 2008 follow-up of the Cork and Kerry Diabetes and Heart Disease Study. Diets were assessed with a standard FFQ. LCA, under the assumption of conditional independence, was used to identify mutually exclusive subgroups with different dietary patterns, based on food group consumption. Setting: Republic of Ireland. Subjects: Men and women aged 50-69 years at baseline (n 923) and at 10-year follow-up (n 320). Results: Three dietary classes emerged: Western, Healthy and Low-Energy. Significant differences in demographic, lifestyle and health outcomes were associated with class membership. Between baseline and follow-up most people remained 'stable' in their dietary class. Most of those who changed class moved to the Healthy class. Higher education was associated with transition to a healthy diet; lower education was associated with stability in an unhealthy pattern. Transition to a healthy diet was associated with higher CVD risk factors at baseline: respondents were significantly more likely to be smokers, centrally obese and to have hypertension (non-significant). Conclusions: LCA is useful for exploring dietary patterns transitions. Understanding the predictors of longitudinal stability/transitions in dietary patterns will help target public health initiatives by identifying subgroups most/least likely to change and most/least likely to sustain a change.

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Cohort Profile: The Cork and Kerry Diabetes and Heart Disease Study

Cited by 77 publications

References 19 publications

Modelling Coronary Heart Disease Mortality declines in the Republic of Ireland, 1985–2006

Modelling Coronary Heart Disease Mortality declines in the Republic of Ireland, 1985–2006

Depressive symptoms, anxiety and well-being among metabolic health obese subtypes

Capturing changes in dietary patterns among older adults: a latent class analysis of an ageing Irish cohort

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