Cohort Profile: The Atlantic Partnership for Tomorrow’s Health (Atlantic PATH) Study

Sweeney, Ellen; Cui, Yunsong; DeClercq, Vanessa; Devichand, Pratima; Forbes, Cynthia C.; Grandy, Scott A.; Hicks, Jason; Keats, Melanie R.; Parker, Louise; Thompson, David M.; Volodarsky, Michael; Yu, Zhijie; Dummer, Trevor J.B.

doi:10.1093/ije/dyx124

Cited by 41 publications

(56 citation statements)

References 9 publications

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“…15 To ensure that our findings were not influenced by any changes in sample attributes across months of survivorship, we also created a variable for and held fixed survivorship time (months elapsed between first cancer diagnosis and survey completion). Current province of residence was coded as 1 for Nova Scotia, 2 for New Brunswick, 3 for Prince Edward Island, 4 for Newfoundland and Labrador).…”

Section: Covariatesmentioning

confidence: 99%

“…15 The participants may not be entirely representative of the general population of Atlantic Canada as the majority of participants in the larger cohort are female which is common in cohort studies.…”

Section: Sensitivity Analysesmentioning

confidence: 99%

“…19 The PHQ-9 is based on the Primary Care Evaluation of Mental Disorders (PRIME-MD) diagnostic instrument and utilizes nine DSM-IV criteria that were measured using a four-point Likert Scale ranging from zero ("not at all"), one ("several days"), two ("more than half the days"), to three ("nearly every day"). [19][20][21] Scores on PHQ-9 range between 0 to 27, with scores under 5 indicating good mental health, 5-9 indicating mild depression symptoms, 10-14 indicating moderate depression symptoms, [15][16][17][18][19] indicating moderately severe depression symptoms, and 20 to 27 indicating severe depression symptoms. To ensure adequate cases, scores on PHQ-9 were binary coded to depict the absence or presence of anxiety symptoms (scores below 5 were coded 0, and those ≥5 were coded 1).…”

Section: Depressionmentioning

confidence: 99%

“…[9][10][11][12] These findings have also been corroborated in a recent survey of PCa survivors in Nova Scotia, New Brunswick, and Prince Edward Island, Canada. 14,15 In brief, participants completed a set of paper and pencil standardized surveys on sociodemographic characteristics, health history, and lifestyle factors, as well as provided physical measures and biological samples. in the development of cancer and chronic disease.…”

Section: Introductionmentioning

confidence: 99%

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Anxiety and depression symptoms in adult males in Atlantic Canada with or without a lifetime history of prostate cancer

2019

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Section: Covariatesmentioning

confidence: 99%

Section: Sensitivity Analysesmentioning

confidence: 99%

Section: Depressionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Anxiety and depression symptoms in adult males in Atlantic Canada with or without a lifetime history of prostate cancer

2019

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“…The Atlantic PATH study recruited 34,169 people aged 30 to 74 years old between 2009 and 2015 from Prince Edward Island, New Brunswick, Nova Scotia, and Newfoundland and Labrador. Details of recruitment and study procedures have been published previously [26]. All participants provided written informed consent.…”

Section: Study Participantsmentioning

confidence: 99%

Diet Quality among Cancer Survivors and Participants without Cancer: A Population-Based, Cross-Sectional Study in the Atlantic Partnership for Tomorrow’s Health Project

Dummer

Spinelli

et al. 2019

Nutrients

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Cancer survivors are encouraged to have a healthy lifestyle to reduce health risks and improve survival. An understanding of health behaviors, such as diet, is also important for informing post-diagnosis support. We investigated the diet quality of cancer survivors relative to participants without cancer, overall and by cancer site and time from diagnosis. A cross-sectional study design within the Atlantic PATH study was used which included 19,973 participants aged 35 to 69 years from Atlantic Canada, of whom 1,930 were cancer survivors. A diet quality score was derived from a food frequency questionnaire. Comparisons of diet quality between cancer survivors and non-cancer controls, cancer site and years since diagnosis were examined in multivariable multi-level models. Cancer survivors had a mean diet quality of 39.1 out of 60 (SD: 8.82) and a higher diet quality than participants without cancer (mean difference: 0.45, 95% CI: 0.07, 0.84) after adjustment for confounders. Odds of high diet quality was greater in breast cancer survivors than participants without cancer (OR = 1.42, 95% CI: 1.06, 1.90), and higher among survivors diagnosed ≤2 years versus >10 years (OR = 1.71, 95% CI: 1.05, 2.80). No other differences by cancer site and years since diagnosis were observed. The difference in diet quality, although statistically significant, is unlikely to be meaningful, suggesting that cancer survivors have similar diet quality as participants without cancer. There was considerable room for dietary improvement regardless of cancer status, highlighting the need for dietary interventions, especially among cancer survivors, who are at higher risk for secondary health problems.

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Psychosocial factors and cancer incidence (PSY‐CA): Protocol for individual participant data meta‐analyses

et al. 2021

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Objectives: Psychosocial factors have been hypothesized to increase the risk of cancer.This study aims (1) to test whether psychosocial factors (depression, anxiety, recent loss events, subjective social support, relationship status, general distress, and neuroticism) are associated with the incidence of any cancer (any, breast, lung, prostate, colorectal, smoking-related, and alcohol-related); (2) to test the interaction between psychosocial factors and factors related to cancer risk (smoking, alcohol use, weight, physical activity, sedentary behavior, sleep, age, sex, education, hormone replacement therapy, and menopausal status) with regard to the incidence of cancer; and (3) to test the mediating role of health behaviors (smoking, alcohol use, weight, physical activity, sedentary behavior, and sleep) in the relationship between psychosocial factors and the incidence of cancer. Methods:The psychosocial factors and cancer incidence (PSY-CA) consortium was established involving experts in the field of (psycho-)oncology, methodology, and epidemiology. Using data collected in 18 cohorts (N = 617,355), a preplanned two-stage individual participant data (IPD) meta-analysis is proposed. Standardized analyses will be conducted on harmonized datasets for each cohort (stage 1), and meta-analyses will be performed on the risk estimates (stage 2). Conclusion:PSY-CA aims to elucidate the relationship between psychosocial factors and cancer risk by addressing several shortcomings of prior meta-analyses.

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Cohort Profile: The Atlantic Partnership for Tomorrow’s Health (Atlantic PATH) Study

Cited by 41 publications

References 9 publications

Anxiety and depression symptoms in adult males in Atlantic Canada with or without a lifetime history of prostate cancer

Anxiety and depression symptoms in adult males in Atlantic Canada with or without a lifetime history of prostate cancer

Diet Quality among Cancer Survivors and Participants without Cancer: A Population-Based, Cross-Sectional Study in the Atlantic Partnership for Tomorrow’s Health Project

Psychosocial factors and cancer incidence (PSY‐CA): Protocol for individual participant data meta‐analyses

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