Cognitive performance on the Alzheimer's Disease Assessment Scale

Doraiswamy, P. Murali; Krishen, Alok; Stallone, Frank; Martin, Wendy L.; Potts, Nicholas; Metz, Alan; DeVeaugh-Geiss, Joseph

doi:10.1212/wnl.45.11.1980

Cited by 34 publications

(20 citation statements)

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“…Previous studies have generally found little or no influence of age, education, or gender on the ADAS-Cog score, although exceptions [2,15] to this general finding have also been reported. The present finding that performance on the Chinese ADAS-Cog was unrelated to education except at the low end (between 0 and 6 years) of the education spectrum is similar to the finding on the MMSE from a community study of 5,297 Chinese subjects [16].…”

Section: Discriminant Item Analysismentioning

confidence: 73%

“…(ii) Objects used for naming are replaced with colored photographs of objects that are more appropriate for our study population. (iii) The scoring of the naming item is simplified in the following manner: a failure is defined as an inability to correctly name an object or a finger within the time limit; the scores (and their corresponding numbers of failures) are 0 (0-2), 1 (3-5), 2 (6-8), 3 (9-11), 4 (12)(13)(14), and 5 (15)(16)(17). (iv) For the praxis item of using an envelope, the subject is asked to write the name only (without writing the address) and to point to the location of stamp placement (instead of actually putting on the stamp).…”

Section: Description Of the Chinese Adas-cogmentioning

confidence: 99%

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The Alzheimer’s Disease Assessment Scale: Findings from a Low-Education Population

Liu

Teng

Chuang

et al. 2001

Dement Geriatr Cogn Disord

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We constructed a Chinese version of the cognitive component of the Alzheimer’s Disease Assessment Scale (ADAS-Cog). In order to accommodate illiteracy, the Chinese version used pictures instead of words for assessing recall and recognition. The Chinese ADAS-Cog was administered to 125 individuals with no dementia, 127 with questionable dementia, and 77 with Alzheimer’s disease (AD). Their age range was 51–92 years and their education range was 0–20 years. The Chinese ADAS-Cog had high internal consistency (Cronbach’s alpha = 0.87) and very high interrater reliability (intraclass correlation coefficient, or ICC, = 0.99) and test-retest reliability (ICC = 0.96). It had high correlations with scores on the Clinical Dementia Rating Scale (Pearson’s r = 0.85), the Cognitive Abilities Screening Instrument (CASI, Pearson’s r = –0.88), and CASI-estimated scores on the Mini-Mental State Examination (Pearson’s r = –0.85). Performance on the Chinese ADAS-Cog was uninfluenced by age or gender, nor by education level except within the low education range of 0–6 years. Its memory items were best for early detection of dementia; its language items were best for monitoring the progression of dementia. This study found that the Chinese ADAS-Cog is a good instrument for use with Chinese AD patients.

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Section: Discriminant Item Analysismentioning

confidence: 73%

Section: Description Of the Chinese Adas-cogmentioning

confidence: 99%

The Alzheimer’s Disease Assessment Scale: Findings from a Low-Education Population

Liu

Teng

Chuang

et al. 2001

Dement Geriatr Cogn Disord

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“…Além disso, os grupos com maiores escolaridades apresentaram desempenhos superiores aos com menos escolaridade (Gráfico 1). Portanto,o escore total, que representa o comprometimento cognitivo apresentado ou a gravidade do quadro demencial, esteve para os analfabetos abaixo das notas de corte apresentadas na literatura 11,13,14,16,[26][27][28] , o que coincide com estudos realizados com outras escalas, como o MEEM 9 e a Adas-cog 29 dentre outras 30,31 .…”

Section: Discussionunclassified

Influência da escolaridade na avaliação neuropsicológica de idosos: aplicação e análise dos resultados da Escala de Mattis para Avaliação de Demência (Mattis Dementia Rating Scale - MDRS)

Foss

Vale

Speciali

2005

Arq. Neuro-Psiquiatr.

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RESUMO: O b j e t i v o:Estimar a influência da baixa escolaridade e do analfabetismo na avaliação das demências através da aplicação da Escala de Mattis para Avaliação de Demência (MDRS). Método: Aplicouse a MDRS em 62 idosos normais (64-77 anos), divididos em cinco grupos, segundo a escolaridade: 15-16 anos, 11-12 anos, 8-9 anos, 4 anos, analfabetos. A MDRS abrange o estudo de 36 itens distribuídos em cinco subescalas, sendo que a soma pode representar o grau de comprometimento cognitivo. R e s u l t a d o s: Observou-se diferença significativa (p<0,05) na escala, no desempenho entre os grupos quanto a escolaridade, em 12 dos itens, nas cinco subescalas ( analfabetos< os demais grupos e os de 15-16 anos> que os de 4 e/ou 8 anos de escolaridade, p≤0,001)e no total de pontos da MDRS (analfabetos 4 and 8 years of schooling, p≤0.001) and the total MDRS score (illiterates< all others and 4 and 8 years < 15-16 years, p <0.001). No significant correlations where found for age and, regarding gender, the differences were significant in only one item Conclusion: Education interfered with individual performance on the MDRS. Illiteracy is a determinant factor of lower MDRS scores that could generate diagnostic errors.

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“…A lower educational level is related to a worse performance in the tests in most of the studies with ADAS (11,25,(27)(28)(29). We observed that there is a significance in the education variable between and within groups.…”

Section: Discussionmentioning

confidence: 99%

The cognitive subscale of the "Alzheimer's Disease Assessment Scale" in a Brazilian sample

Schultz

Siviero

Bertolucci

2001

Braz J Med Biol Res

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The cognitive subscale of the Alzheimers Disease Assessment Scale (ADAS-Cog) is widely used for the evaluation of dementia and is very popular in dementia drug trials because of the characteristics of the scale. The objective of the present study was to adapt the ADASCog for use for the Brazilian population. A major problem is that education is variable, a fact that may influence performance in cognitive evaluation. This study was conducted on a control group (CG) of 96 subjects (25 males and 71 females aged 68 ± 8.6 years) and on 44 Alzheimers disease (AD) patients (19 males and 25 females aged 72 ± 6.4 years) with mild dementia (Clinical Dementia Rating score 1). For statistical analysis groups were divided into three educational levels: I, 0-4 years of schooling (65 CG/20 AD); II, 5-11 years of schooling (19 CG/7 AD), and III, 12 or more years of schooling (12 CG/17 AD). The battery was applied according to original instructions. Total mean score for CG and AD was 10.9 and 22.9 for level I, 7.8 and 22.4 for level II, and 6.2 and 15.4 for level III, respectively. These results indicate that our version of the ADAS-Cog is useful to identify mild dementia, though there may be an overlapping when comparing high education demented with low education non-demented subjects.

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Cognitive performance on the Alzheimer's Disease Assessment Scale

Cited by 34 publications

References 0 publications

The Alzheimer’s Disease Assessment Scale: Findings from a Low-Education Population

The Alzheimer’s Disease Assessment Scale: Findings from a Low-Education Population

Influência da escolaridade na avaliação neuropsicológica de idosos: aplicação e análise dos resultados da Escala de Mattis para Avaliação de Demência (Mattis Dementia Rating Scale - MDRS)

The cognitive subscale of the "Alzheimer's Disease Assessment Scale" in a Brazilian sample

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