Cognitive Function in People With Chronic Illness: Inflammatory Bowel Disease and Irritable Bowel Syndrome

Attree, Elizabeth A.; Dancey, Christine P.; Keeling, Deborah; Wilson, C. D.

doi:10.1207/s15324826an1002_05

Cited by 55 publications

(59 citation statements)

References 45 publications

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“…The disease disturbs adolescents' quality of life [25,36,37] , may have negative consequences for education and school functioning [38,39] , and may be a cause of difficulties in employment, such as finding or maintaining a desired job [40][41][42] . Furthermore, adolescents with severe IBD have disturbed sleep and are overtired tion to even minor cognitive problems that may be aggravated during the growth process [43,52,53] .…”

Section: Psychological Symptoms In Ibdmentioning

confidence: 99%

Psychiatric comorbidity in the treatment of patients with inflammatory bowel disease

Filipović¹,

Filipović²

2014

WJG

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Ulcerative colitis and Crohn's disease, commonly known as inflammatory bowel disease (IBD), draw attention from specialists of various disorders, including gastroenterology, psychiatry, and radiology. The involvement of a cortical influence in the brain-gut axis as well as the interaction of the hypothalamic-pituitary-adrenal axis and the peripheral nervous system provide an initial explanation of the psychological symptoms associated with IBD. The involvement of structures the limbic system, such as the anterior cingulate cortex, the prefrontal cortex, and the amygdala, paves the way for the discovery of the mechanisms underlying depression depression, anxiety, alexithymia, personality traits, and other psychological impairments following the onset of IBD. Psychiatric therapy in IBD patients is almost as important as the gastroenterological approach and consists of pharmacological treatment and psychotherapy. Neither of the available psychiatric treatment methods is considered the golden standard because both methods have side effects, and psychotropic medication can provoke the worsening of IBD symptoms. Thus, both approaches must be applied with awareness of the possibility of side effects. We suggest that psychiatrists and gastroenterologists work together to reach a consensus on IBD therapy to ensure success and to reduce side effects and relapse to the lowest possible rates.© 2014 Baishideng Publishing Group Co., Limited. All rights reserved.Key words: Inflammatory bowel disease; Psychiatry; Treatment; Personality traits; Depression; Anxiety Core tip: The involvement of a dysfunction of brain-gut interactions in the pathogenesis of inflammatory bowel disease (IBD) is represented by a dysfunction of the autonomic nervous system, an abnormal hypothalamicpituitary-adrenal axis and cholinergic anti-inflammatory pathway, a deleterious effect of stress and depression, an abnormal coupling of the prefrontal cortex-amygdaloid complex, and an abnormal relation between the microbiota and the brain as pro-inflammatory factors. New investigations have provided a critical link between forebrain changes and abdominal pain independent of active disease and drug treatment, providing a potential basis for an explanation of the psychological symptoms and brain influence in the pathogenesis of IBD.

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Section: Psychological Symptoms In Ibdmentioning

confidence: 99%

Psychiatric comorbidity in the treatment of patients with inflammatory bowel disease

Filipović¹,

Filipović²

2014

WJG

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“…Attree et al [19] recently reported that IBS subjects had a full and verbal IQ slightly lower than controls and a deficit in verbal vs performance IQ. Differences in our results may be due to differences in the study sample.…”

Section: Discussionmentioning

confidence: 99%

“…Differences in our results may be due to differences in the study sample. We studied a convenience sample of subjects with IBS covering the whole spectrum of the disease, without interest in psychological management or prior psychiatric diagnosis, while Attree et al [19] included a group of IBS subjects who had previously expressed an interest in participating in research at a school of psychology. Indeed, our finding that consulters displayed a slightly lower full and verbal IQ than non-consulters points to this explanation.…”

Section: Discussionmentioning

confidence: 99%

“…IQ has been found to be associated with health [16] and longevity [17] , likely through an influence on health knowledge and health behavior [18] . Attree et al [19] recently found a lower IQ in IBS subjects vs controls. Rational intelligence might enhance one's ability to identify environmental factors precipitating bowel symptoms and change one's lifestyle accordingly.…”

Section: Introductionmentioning

confidence: 93%

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Constructive thinking, rational intelligence and irritable bowel syndrome

Rey¹,

Ortega²,

Alonso³

et al. 2009

WJG

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AIM:To evaluate rational and experiential intelligence in irritable bowel syndrome (IBS) sufferers. METHODS:We recruited 100 subjects with IBS as per Rome Ⅱ criteria (50 consulters and 50 non-consulters) and 100 healthy controls, matched by age, sex and educational level. Cases and controls completed a clinical questionnaire (including symptom characteristics and medical consultation) and the following tests: rationalintelligence (Wechsler Adult Intelligence Scale, 3rd edition); experiential-intelligence (Constructive Thinking Inventory); personality (NEO personality inventory); psychopathology (MMPI-2), anxiety (state-trait anxiety inventory) and life events (social readjustment rating scale). Analysis of variance was used to compare the test results of IBS-sufferers and controls, and a logistic regression model was then constructed and adjusted for age, sex and educational level to evaluate any possible association with IBS. RESULTS:No differences were found between IBS cases and controls in terms of IQ (102.0 ± 10.8 vs 102.8 ± 12.6), but IBS sufferers scored significantly lower in global constructive thinking (43.7 ± 9.4 vs 49.6 ± 9.7). In the logistic regression model, global constructive thinking score was independently linked to suffering from IBS ], without significant OR for total IQ. CONCLUSION:IBS subjects do not show lower rational intelligence than controls, but lower experiential intelligence is nevertheless associated with IBS.

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“…The brain-gut axis appears to have a major importance of cognitive performance. The psychiatric comorbidity has also impact in the neurocognitive functioning [15,35].…”

Section: Neuropsychological Indings In Ibsmentioning

confidence: 99%

Psychiatric Comorbidities in Irritable Bowel Syndrome (IBS)

Stănculete¹

2016

Irritable Bowel Syndrome - Novel Concepts for Research and Treatment

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F" lot of research has pointed out that irritable bowel syndrome (I"S is a multifactorial illness involving visceral hypersensitivity, alteration of communication between the enteric nervous system (ENS and central nervous system (CNS , increased intestinal permeability, minimal intestinal inlammation, and altered intestinal microlora. Psychological, social, and genetic factors appear to be important in the development of I"S symptomatology through several mechanisms. This chapter addresses the relationships between irritable bowel syndrome (I"S and psychiatric comorbidities. The aim of this chapter is to provide an overview of explanatory hypothesis and to describe a variety of approaches which integrate the vast research data about I"S and psychiatric comorbidities, including genetic, brain imaging, and neuropsychological indings. The section of this chapter which overlooks the psychotropic treatment reviews the comparative eicacy of various drugs.

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Cognitive Function in People With Chronic Illness: Inflammatory Bowel Disease and Irritable Bowel Syndrome

Cited by 55 publications

References 45 publications

Psychiatric comorbidity in the treatment of patients with inflammatory bowel disease

Psychiatric comorbidity in the treatment of patients with inflammatory bowel disease

Constructive thinking, rational intelligence and irritable bowel syndrome

Psychiatric Comorbidities in Irritable Bowel Syndrome (IBS)

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