Psychiatric Comorbidities in Irritable Bowel Syndrome (IBS)

Stănculete, Mihaela Fadgyas

doi:10.5772/66301

Cited by 3 publications

(2 citation statements)

References 39 publications

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“…Long-term effects on exposure to stress in early life have shown epigenetic changes. [ 15 ] The most common physical comorbidity was diabetes mellitus (37.8%). A study comparing the prevalence of diabetes mellitus in patients with IBS and healthy controls showed that the incidence of DM is significantly higher in IBS patients.…”

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confidence: 99%

A follow-up study of anxiety and depressive symptoms in irritable bowel syndrome

Banerjee,

Sarkhel,

Dhali

et al. 2024

Indian Journal of Psychiatry

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Background: Irritable bowel syndrome (IBS) is a functional gastrointestinal (GI) disorder and is closely linked to stress. Psychiatric morbidities such as anxiety and depression are common in IBS. Long-term follow-up studies on anxiety and depressive symptoms in IBS and the impact of treatment are lacking in the Indian scenario. Aims: This study aimed to assess the various subtypes of IBS according to the Rome IV criteria, assess anxiety and depressive symptoms in patients with IBS at baseline and also at various phases of follow-up over one year, and see the impact of the treatment of both IBS and associated anxiety and depressive symptoms if present, in the severity of IBS and other psychiatric symptoms. Materials and Methods: Patients with IBS, aged between 18 and 65 years, were enrolled for the study. Subtypes and severity of IBS were assessed. Anxiety and depressive symptoms were assessed by the Hamilton Rating Scale for Anxiety (HAM-A) and the Hamilton Rating Scale for Depression (HAM-D), respectively. The patients were treated with conventional treatment of IBS with concomitant treatment of anxiety and depressive symptoms and were followed up for 1 year. Results: Thirty-seven patients completed a 1-year follow-up. The mean age was 38.4 ± 11.6 years. The majority were males (81%), and IBS-D (84%) was the most common subtype. Stressful life events (67.6%) and chronic stressors (64.9%) were present in the majority of the patients. The patients had moderate-to-severe anxiety at baseline (HAM-A score 27.8 ± 6.4) and moderate-to-severe depression at baseline (HAM-D score 19.7 ± 6.6). The improvement over 1 year was statistically significant (P = 0.000, two-tailed). A positive correlation between the severity score of IBS and HAM-D (r = 0.604) and HAM-A (r = 0.536) scores was present. Conclusion: There is a high prevalence of anxiety and depression in patients with IBS. With adequate treatment of both IBS and concomitant anxiety-depressive symptoms, there is a significant decrease in the severity of IBS, anxiety, and depression.

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Section: Discussionmentioning

confidence: 99%

A follow-up study of anxiety and depressive symptoms in irritable bowel syndrome

Banerjee,

Sarkhel,

Dhali

et al. 2024

Indian Journal of Psychiatry

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“…A study by Roy conducted over 366 healthy control females age between 35-50 years [mean age(41.49±3.80)] found psychiatric morbidities about 28.1% among which major depressive disorder (11.2%) followed by generalized anxiety disorder (9.8%), obsessive compulsive disorder (2.7%), panic disorder (1.6%), somatization disorder (1.6%) and conversion disorder (1.1%) 12. Another study conducted in same place by Khan over 110 healthy controls age between 18-60 years (majority 45.5% of age 18-30) and found psychiatric morbidities about 16.4 % among which major depressive disorder 8.2 %, anxiety disorder 4.5 5 and somatization disorder 3.6 % 13. …”

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confidence: 95%

Psychiatric morbidity in psoriasis patients

Biswas,

Roy,

Roy

et al. 2022

Bang J Psychiatry

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Psoriasis is one of the established chronic dermatological disorders which exacerbate and triggers in stressful life condition. Sometimes it may cause disfigurement that enhances stress. In long run majority of patients get depressed and also show symptoms of anxiety and depressive disorder. This was a cross sectional study, conducted in the department of psychiatry in collaboration with the department of dermatology and venereology of Sylhet MAG Osmani Medical College Hospital, Sylhet, Bangladesh during the period from January 2013 to December 2013 to evaluate the psychiatric morbidity among the psoriasis patients and healthy controls and compare with them. For this purpose, 50 patients with psoriasis of 18 years to 65 years of age were included and categorized as group A where another 50 age and sex matched healthy individuals were included as group B by consecutive, convenient (non-probability) sampling technique. Patients having any past or family history of psychiatric disorder, substance abuse, history of any chronic medical illness, history of long term corticosteroid therapy and obese patients were excluded from the study. After taking informed consent respondents were interviewed using data collection sheet containing socio-demographic and other information which was structured and fix response type. A General Health Questionnaire (GHQ) 12 Bangla version was supplied to the patients and advised to fill up the questionnaire. Those who scored 15 or above points were further evaluated by mental state examination and Diagnostic and Statistical Manual of Mental Disorders (DSM) IV Text Revision (TR) criteria for the diagnosis of psychiatric disorders. All psychiatric disorders were diagnosed clinically and verified by consultant psychiatrist. Ethical issues were maintained properly and an informed written consent was taken from every patient. After collecting data, editing was done manually and was analyzed with statistical package for social sciences (SPSS) version 21. The results showed that, the mean age of the respondents was 36.5 (SD±13.5) and control 36.0 (SD±14.4) years which was almost identical to control group (p=0.914). Psychiatric morbidity was most frequent in psoriasis group (62.0%) as compared to control group (20.0%) (p<0.001). The most common psychiatric disorder was major depressive disorder (32.0%) followed by generalized anxiety disorder (18.0%), dysthymic disorder (6.0%), somatoform disorder not otherwise specified (NOS) (4.0%) and adjustment disorder (2.0%). The results of this study suggest that a significant number of patients with Psoriasis suffer from psychiatric disorder than healthy control group. Bang J Psychiatry 2022;36(2): 27-34

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