Cognitive behavior therapy combined with exercise for adults with chronic diseases: Systematic review and meta-analysis.

Bernard, Paquito; Romain, Ahmed Jérôme; Caudroit, Johan; Chevance, Guillaume; Carayol, Marion; Gourlan, Mathieu; Dancause, Kelsey Needham; Moullec, Grégory

doi:10.1037/hea0000578

Cited by 50 publications

(38 citation statements)

References 92 publications

(115 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…While the majority of these studies have been done to compare the effectiveness of BT to exercise interventions, fewer studies have been employed to examine the combined effect of exercise and BT (BT+Ex). Researchers have hypothesized that BT+Ex may augment the effectiveness of treatment [20]. Ernst et al [21] hypothesized that the exercise-induced upregulation of brain-derived neurotrophic factor (BDNF) promotes brain neurogenesis, resulting in a reduction of symptoms associated with depression and anxiety [21].…”

Section: Introductionmentioning

confidence: 99%

The Combined Effect of Exercise and Behavioral Therapy for Depression and Anxiety: Systematic Review and Meta-Analysis

Bourbeau

Moriarty

Ayanniyi

et al. 2020

Behavioral Sciences

View full text Add to dashboard Cite

Behavioral therapy (BT) and exercise are efficacious treatments for depression and anxiety when employed separately. The combination of BT and exercise (BT+Ex) may augment improvements but the combined effect of these therapies is not fully elucidated. The purpose of this meta-analysis was to determine if BT+Ex yielded a significant reduction in depression and anxiety symptoms compared to BT alone (BT). Randomized controlled studies published prior to September 2019 were searched among several databases (PUBMED, MEDLINE, PsychArticle, and Cochrane Central Register of Clinical Trials). Studies that measured depression and anxiety symptoms following BT+Ex vs. BT were extracted and analyzed. The effect of these therapies on depression and anxiety were analyzed. Subgroup analyses were performed to evaluate the effect of exercise intensity (moderate and high), exercise type (aerobic and combined exercise), and baseline levels of depression. The moderating effects of gender, age, and treatment duration were performed. Data were extracted from 18 studies (1686 participants, mean age = 47 years, 65% female). There was a significant effect of BT+Ex on symptoms of depression. The effect of BT+Ex was significant for moderate intensity exercise and elevated baseline levels of depression. Age moderated the effect for depression. There was a significant effect of BT+Ex on depressive symptoms in humans. Exercise intensity and elevated depressive symptoms may play a role in the effect of exercise.

show abstract

Section: Introductionmentioning

confidence: 99%

The Combined Effect of Exercise and Behavioral Therapy for Depression and Anxiety: Systematic Review and Meta-Analysis

Bourbeau

Moriarty

Ayanniyi

et al. 2020

Behavioral Sciences

View full text Add to dashboard Cite

show abstract

“…Of these, eight papers were rejected because they were not about CBT, 11 were not meta-analyses, 25 were not about anxiety disorders, 31 were limited in their population scope, two were not about treatment efficacy, five were limited to Internet or computer-based intervention, and six were about CBT-VRexp or MBT. Of the eight remaining papers, one was rejected because it was limited in scope (group therapy for PTSD; Schwartze et al, 2019), one was too restrictive on the measure of outcome to allow comparisons (remission rate; Springer et al, 2018), two studied the effect of added interventions to CBT (Bernard et al, 2018;Marker and Norton, 2018), and two were limited to primary care settings without information about specific anxiety disorders (Zhang et al, 2019a,b). Since Barry et al (2018) did not provide information about RCTs, we favored Carpenter et al 2018for our study (see Supplementary Material 3).…”

Section: Resultsmentioning

confidence: 99%

The Adoption of New Treatment Modalities by Health Professionals and the Relative Weight of Empirical Evidence in Favor of Virtual Reality Exposure Versus Mindfulness in the Treatment of Anxiety Disorders

Nolet

Corno

Bouchard

2020

Front. Hum. Neurosci.

View full text Add to dashboard Cite

Anxiety disorders are among the most prevalent mental disorders, and cognitivebehavioral therapy (CBT) with exposure exercises is considered as the gold-standard psychological intervention. New psychotherapeutic modalities have emerged in the last decade and, among them, mindfulness has been rapidly adopted by therapists. The adoption rate is slower for the use of virtual reality (VR) to conduct exposure. The goal of the present position paper is to contrast, for the treatment of anxiety disorders, the weight of empirical evidences supporting the use of exposure in VR with the use of mindfulness-based therapy (MBT). Based on the most recent meta-analyses, we found that CBT with exposure conducted in VR was more thoroughly researched and supported than MBT, receiving validation from roughly twice as many studies with high control (i.e., randomized, active controls with clinical samples). However, this conclusion is nuanced by reviewing gaps in the literature for both therapies. Potential factors influencing clinicians' choice of treatment and suggestions for future research directions are proposed.

show abstract

“…7 Therapeutic lifestyle changes that target diet and exercise are known to positively influence depressed mood. 34,35 We have previously shown that standard cardiac rehabilitation is effective in not only reducing mortality risk but also in reducing depression symptoms in HF, 7 and that other forms of behavioral interventions favorably affect the somatic/affective but not the cognitive/affective depressive symptoms. 17 Given the elevated IL-6, TNF-R1, and sST2 levels in stage B HF patients with both T2DM and depressed mood, additional attention and interventions to forestall potential transition to symptomatic stage C HF may be warranted.…”

Section: Resultsmentioning

confidence: 99%

“…As noted above, depressive symptoms and depressed mood are significant predictors of morbidity and mortality in cardiac and noncardiac populations . Therapeutic lifestyle changes that target diet and exercise are known to positively influence depressed mood . We have previously shown that standard cardiac rehabilitation is effective in not only reducing mortality risk but also in reducing depression symptoms in HF, and that other forms of behavioral interventions favorably affect the somatic/affective but not the cognitive/affective depressive symptoms …”

Section: Discussionmentioning

confidence: 99%

Depressive symptoms in asymptomatic stage B heart failure with Type II diabetic mellitus

Mills

Taub

Lunde

et al. 2019

Clinical Cardiology

View full text Add to dashboard Cite

Background The presence of concomitant Type II diabetic mellitus (T2DM) and depressive symptoms adversely affects individuals with symptomatic heart failure (HF). Hypothesis In presymptomatic stage B HF, this study hypothesized the presence of greater inflammation and depressive symptoms in T2DM as compared to non‐T2DM Stage B patients. Methods This cross‐sectional study examined clinical parameters, inflammatory biomarkers, and depressive symptoms in 349 T2DM and non‐T2DM men with asymptomatic stage B HF (mean age 66.4 years ±10.1; range 30‐91). Results Fewer diabetic HF patients had left ventricular (LV) systolic dysfunction ( P < .05) although more had LV diastolic dysfunction ( P < .001). A higher percentage of T2DM HF patients were taking ACE‐inhibitors, beta‐blockers, calcium channel blockers, statins, and diuretics ( P values < .05). T2DM HF patients had higher circulating levels of interleukin‐6 (IL‐6) ( P < .01), tumor necrosis factor‐alpha ( P < .01), and soluble ST2 (sST2) ( P < .01) and reported more somatic/affective depressive symptoms (Beck Depression Inventory II) ( P < .05) but not cognitive/affective depressive symptoms ( P = .20). Among all patients, in a multiple regression analysis predicting presence of somatic/affective depressive symptoms, sST2 ( P = .026), IL‐6 ( P = .010), B‐type natriuretic peptide ( P = .016), and sleep (Pittsburgh Sleep Quality Index [ P < .001]) were significant predictors (overall model F = 15.39, P < .001, adjusted R 2 = .207). Conclusions Somatic/affective but not cognitive/affective depressive symptoms are elevated in asymptomatic HF patients with T2DM patients. Linkages with elevated inflammatory and cardiac relevant biomarkers suggest shared pathophysiological mechanisms among T2DM HF patients with somatic depression, and these conditions are responsive to routine interventions, including behavioral. Copyright © 2019 John Wiley & Sons, Ltd.

show abstract

Cognitive behavior therapy combined with exercise for adults with chronic diseases: Systematic review and meta-analysis.

Abstract: Therapy combined with physical exercise for depression, anxiety, fatigue and pain in adults with chronic diseases: systematic review and meta-analysis. Health Psychology (accepted) 1 Declaration of interestAll authors declare that they have no competing interests for this work.

Cited by 50 publications

References 92 publications

The Combined Effect of Exercise and Behavioral Therapy for Depression and Anxiety: Systematic Review and Meta-Analysis

The Combined Effect of Exercise and Behavioral Therapy for Depression and Anxiety: Systematic Review and Meta-Analysis

The Adoption of New Treatment Modalities by Health Professionals and the Relative Weight of Empirical Evidence in Favor of Virtual Reality Exposure Versus Mindfulness in the Treatment of Anxiety Disorders

Depressive symptoms in asymptomatic stage B heart failure with Type II diabetic mellitus

Contact Info

Product

Resources

About