Cognition in relation to independency in older, comorbid stroke patients in a stroke unit

Huijben-Schoenmakers, Marleen; Rademaker, A.; Scherder, E.J.A.

doi:10.1002/gps.4518

Cited by 10 publications

(6 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, regression analyses model including MoCA's cognitive domains showed low sensitivity and specificity. The results are partially in line with other studies showing that cognitive domains like attention, language (29), executive functions, and delayed reproduction (6) might have an impact on ADLs, highlighting executive functions as the most important. Decline in executive and memory functions is usually related to age (30).…”

Section: Discussionsupporting

confidence: 91%

“…However, in that study cognitive function was not identified as a significant variable. In contrast, cognitive functions assessed with a different cognitive tool was associated with ADL dependence (6). Cognitive malfunctioning is known to be related to older age (33, 34).…”

Section: Discussionmentioning

confidence: 99%

“…Regarding dependent variables, the BI was dichotomized and coded as “dependent-1” (<95) and “independent-0” (>95) (17, 18). The independent variables were chosen according to previous literature (6–8) and clinical experience. Age, the MoCA and the NIHSS scores were included as continuous variables in the models.…”

Section: Methodsmentioning

confidence: 99%

“…Studies performed on a subacute stroke population showed a positive association between impaired cognitive function assessed with the MoCA and a high level of global disability (5). Poor executive and memory functions were positively associated with dependence in activities of daily living (ADL) (6). However, explanatory factors for favorable ADL outcomes 3 to 12 month post stroke were stroke localization (7), younger age, less severity of neurological deficits, and good function in the upper extremities (7, 8).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Feasibility of Cognitive Functions Screened With the Montreal Cognitive Assessment in Determining ADL Dependence Early After Stroke

et al. 2018

View full text Add to dashboard Cite

Objective: To investigate the feasibility of assessing cognitive function using the Montreal Cognitive Assessment (MoCA) given 36–48 h post stroke to explain dependence in activities of daily living (ADL).Methods: This is a cross-sectional, exploratory study. Cognitive function and basic ADL were assessed with the MoCA and the Barthel Index (BI), respectively, within 36–48 h of admission. Neurological functions were assessed with the National Institute of Health Stroke Scale (NIHSS) upon admittance to the hospital. Binary logistic regression analyses were performed to assess the feasibility of the MoCA in explaining ADL dependence.Results: Data were available for 550 patients (42% females, mean age 69 years). Moderate correlations (rs > +0.30, p < 0.001) were found between the total score on the BI, MoCA, and visuospatial/executive functions. The regression analysis model including only MoCA as an independent variable had a high sensitivity for explaining ADL dependence. However, the model with independent variables of MoCA, NIHSS, and age had the best area under the curve value (0.74).Conclusions: Cognitive functions assessed with the MoCA partly explain ADL dependence 36–48 h post stroke. Stroke-related neurological deficits and age should be additional considerations.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Feasibility of Cognitive Functions Screened With the Montreal Cognitive Assessment in Determining ADL Dependence Early After Stroke

et al. 2018

View full text Add to dashboard Cite

show abstract

“…ICH is associated with motor damage [ 25 , 26 ] and cognitive impairments [ 27 ] that may be closely related to oxidative stress [ 28 ]. Our current results show that ICH generates locomotor and exploratory damage (OF), which is maintained for up to 3 days after injury.…”

Section: Discussionmentioning

confidence: 99%

Green Tea and Red Tea from Camellia sinensis Partially Prevented the Motor Deficits and Striatal Oxidative Damage Induced by Hemorrhagic Stroke in Rats

2018

View full text Add to dashboard Cite

Green tea from Camellia sinensis plays a well-established neuroprotective role in several neurodegenerative diseases, including intracerebral hemorrhage (ICH). However, the other teas of the same plant do not have their properties well understood; but they can be as effective as green tea as an alternative therapy. In this study, we investigated the effects of supplementation with green tea and red tea from Camellia sinensis on motor deficits and striatum oxidative damage in rats submitted to hemorrhagic stroke (ICH). Male Wistar rats were supplemented with green tea, red tea, or vehicle for 10 days prior to ICH induction. After injury, the rats were submitted to motor tests (open field for locomotion, rotarod for balance, and neurological deficit scale (NDS)) 1, 3, and 7 days after ICH induction, while the tea supplementation was maintained. Subsequently, the rats were euthanized to striatal tissue dissection for biochemical analyzes (lipid peroxidation, reactive oxygen species, glutathione levels, and total antioxidant capacity). ICH caused locomotor and balance deficits, as well as increased the neurological deficit (NDS). Only red tea prevented locomotor deficits after injury. Green tea and red tea prevented balance deficits on the seventh day after ICH. On NDS evaluation, green tea presented a better neuroprotection than red tea (until day 3 after ICH injury). In addition, ICH increased reactive oxygen species and lipid peroxidation levels, without altering antioxidant markers. Green and red teas were effective in decreasing the lipid peroxidation levels. Therefore, green and red teas partially prevented the motor deficits and striatal oxidative damage induced by ICH. Based on our results, we can consider that the two teas seem to be equally effective to prevent motor deficits and striatal oxidative damage induced by hemorrhagic stroke in rats.

show abstract

A Meta-Analysis of Neuropsychological Predictors of Outcome Following Stroke and Other Non-Traumatic Acquired Brain Injuries in Adults

et al. 2020

View full text Add to dashboard Cite

Cognition in relation to independency in older, comorbid stroke patients in a stroke unit

Abstract: From a clinical point of view, we suggest combining physical and cognitive training from the very early phase of recovery.

Cited by 10 publications

References 40 publications

Feasibility of Cognitive Functions Screened With the Montreal Cognitive Assessment in Determining ADL Dependence Early After Stroke

Feasibility of Cognitive Functions Screened With the Montreal Cognitive Assessment in Determining ADL Dependence Early After Stroke

Green Tea and Red Tea from Camellia sinensis Partially Prevented the Motor Deficits and Striatal Oxidative Damage Induced by Hemorrhagic Stroke in Rats

A Meta-Analysis of Neuropsychological Predictors of Outcome Following Stroke and Other Non-Traumatic Acquired Brain Injuries in Adults

Contact Info

Product

Resources

About