Coffee and Tea Group Contribute the Most to the Dietary Total Antioxidant Capacity of Older Adults: A Population Study in a Medium-Sized Brazilian City

Nascimento-Souza, Mary Anne; Paiva, Pedro Gontijo de; Silva, Alessandra da; Duarte, Maria Sônia Lopes; Ribeiro, Andréia Queiróz

doi:10.1080/07315724.2020.1823281

Cited by 6 publications

(4 citation statements)

References 64 publications

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“…Finally, coffee, which is rich in phenolic compounds, is a significant source of dietary antioxidants [ 22 , 23 , 24 ], and has a higher antioxidant capacity than tea [ 70 , 71 ]. A higher plasma or dietary total antioxidant capacity is associated with lower likelihoods of dyslipidemia, hyperglycemia, and hypertension [ 72 , 73 , 74 ].…”

Section: Discussionmentioning

confidence: 99%

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Metabolic Disorders in Patients with Chronic Hepatitis B Virus Infection: Coffee as a Panacea? (ANRS CO22 Hepather Cohort)

et al. 2022

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People living with chronic hepatitis B virus (HBV) infection are at high risk of liver disease progression, which is positively associated with metabolic disorders, but inversely associated with dyslipidemia. Diet, including dietary antioxidants, is a lever of metabolic disorder management. In particular, elevated coffee consumption is associated with different metabolic outcomes in the general population. We aimed to test whether such associations occur in HBV-infected people. Based on cross-sectional data from the ANRS CO22 Hepather cohort, we performed logistic regression models with (i) dyslipidemia, (ii) hypertension, and (iii) diabetes as outcomes, and with demographic, clinical, and socio-behavioral (including coffee consumption) data as explanatory variables. Among 4746 HBV-infected patients, drinking ≥3 cups of coffee per day was associated with a higher risk of dyslipidemia (adjusted odds ratio [95% confidence interval] 1.49 [1.10–2.00], p = 0.009) and a lower risk of hypertension (0.64 [0.50–0.82], p = 0.001). It was not associated with diabetes. Elevated coffee consumption was associated with a higher risk of dyslipidemia and a lower risk of hypertension in HBV-infected patients, two effects expected to be associated with favorable clinical outcomes. Further studies should test whether such metabolic benefits translate into reduced mortality risk in this population.

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Section: Discussionmentioning

confidence: 99%

“…Most possess antioxidant (and anti-inflammatory) properties [ 21 ]. Coffee and tea constitute two main food sources of polyphenols [ 22 , 23 , 24 ]. In the general population, coffee consumption is associated with higher total cholesterol levels.…”

Section: Introductionmentioning

confidence: 99%

Metabolic Disorders in Patients with Chronic Hepatitis B Virus Infection: Coffee as a Panacea? (ANRS CO22 Hepather Cohort)

et al. 2022

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“…According to arrhythmic profile, the slightest decrease was exhibited in paroxysmal supraventricular tachycardia, for both groups (73.90% for patients in group I and 82.37% for group II) and the most significant decrease was revealed in sinus bradycardia (64.66%), in the dyslipidemia group and also in atrial flutter (66.58%) in non-dyslipidemics, all compared with the control group. GPx, as a biomarker, demonstrated, by its decrease, in cardiac arrhythmic pathology, the existence of oxidative stress, which can influence the electrochemical processes generating non-structural arrhythmic pathophysiological disorders in young individuals (2,3,(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25).…”

Section: Discussionmentioning

confidence: 99%

Decrease of glutathione peroxidase in arrhythmic cardiac pathology in young individuals and its therapeutic implications

et al. 2022

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Glutathione peroxidase (GPx), as an antioxidant enzyme, is involved in the regulation of processes that cause cellular oxidative stress, with implications in various pathologies. The aim of the present study was to evaluate GPx variations in patients with arrhythmic, non-structural cardiac disorders. The research was performed on 120 patients, with a mean age of 33 years old, divided into 3 equal groups, of which 2 groups included patients with cardiac arrhythmias, the first group, associated with dyslipidemia and the second one, without dyslipidemia, and a control group consisting of healthy individuals. The method for determining GPx was based on the GPx enzyme catalysis reaction of the reduced glutathione (GSH) oxidation reaction by cumene hydroperoxide. The results revealed that GPx variation was decreased in patients with cardiac arrhythmias, with or without dyslipidemia, up to 66 and 74% of mean control values, respectively, the differences being statistically significant, showing the existence of an oxidative stress imbalance, that may be involved in triggering arrhythmogenic electrochemical mechanisms. The GPx deficiency determined in relation to cardiac arrhythmias was in dyslipidemic and non-lipidemic patients as follows: 29-35% in sinus bradycardia, 31-35% in associated cardiac arrhythmias, 30-33% in sinus tachycardia, 27-33% in atrial fibrillation, 32-33% in atrial flutter, 27-32% in atrial extrasystolic arrhythmia, 28-30% in ventricular extrasystolic arrhythmia and 18-26% in paroxysmal supraventricular tachycardia. Collectively, the results revealed that GPx, an antioxidant enzyme, is a specific biomarker, whose decrease indicated the existence of oxidative stress in young individuals with cardiac arrhythmias and its involvement in arrhythmogenic electrochemical processes. In addition, GPx deficiencies were between 18-35% in all types of cardiac arrhythmias, the highest being recorded in sinus bradycardia and the lowest in paroxysmal supraventircular tachycardia. Furthermore, the oxidative stress favored by the decrease of GPx induced lipid oxidation, regardless of the presence or absence of dyslipidemia, which triggered the formation of anti-lipid antibodies and a subclinical endothelial aggression, with early atherosclerotic potential. GPx evaluation may argue for the existence of oxidative stress in non-structural cardiac arrhythmias, and by its proper correction (antioxidants), prophylaxis of atherogenic dysfunction.

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“…The main polyphenol species were PAs (729.5 mg/day) and flavonoids (444.7 mg/day), with 292 polyphenols identified, while the highest intake of individual compounds was CGA and its isomers from the HCAs in coffee (i.e., 5‐caffeoylquinic acid, 4‐caffeoylquinic acid, and 3‐caffeoylquinic acid). The main dietary sources of total polyphenols were coffee (45.8%), legumes (32.8%), and polenta (1.3%) (Nascimento‐Souza et al., 2021). The daily polyphenol intake by European adolescents was found to be 167−564 mg/day.…”

Section: Dietary Sources Absorption and Bioavailability Of Pasmentioning

confidence: 99%

Research progress regarding the effect and mechanism of dietary phenolic acids for improving nonalcoholic fatty liver disease via gut microbiota

Deng

Xue

et al. 2023

Comp Rev Food Sci Food Safe

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Phenolic acids (PAs), a class of small bioactive molecules widely distributed in food and mainly found as secondary plant metabolites, present significant advantages such as antioxidant activity and other health benefits. The global epidemic of nonalcoholic fatty liver disease (NAFLD) is becoming a serious public health problem. Existing studies showed that gut microbiota (GM) dysbiosis is highly associated with the occurrence and development of NAFLD. In recent years, progress has been made in the study of the relationship among PA compounds, GM, and NAFLD. PAs can regulate the composition and functions of the GM to promote human health, while GM can increase the dietary sources of PAs and improve its bioavailability. This paper discussed PAs, GM, and their interrelationship while introducing several representative dietary PA sources and examining the absorption and metabolism of PAs mediated by GM. It also summarizes the effect and mechanisms of PAs in improving and regulating NAFLD via GM and their metabolites. This helps to better evaluate the potential preventive effect of PAs on NAFLD via the regulation of GM and expands the utilization of PAs and PA‐rich food resources.

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Coffee and Tea Group Contribute the Most to the Dietary Total Antioxidant Capacity of Older Adults: A Population Study in a Medium-Sized Brazilian City

Cited by 6 publications

References 64 publications

Metabolic Disorders in Patients with Chronic Hepatitis B Virus Infection: Coffee as a Panacea? (ANRS CO22 Hepather Cohort)

Metabolic Disorders in Patients with Chronic Hepatitis B Virus Infection: Coffee as a Panacea? (ANRS CO22 Hepather Cohort)

Decrease of glutathione peroxidase in arrhythmic cardiac pathology in young individuals and its therapeutic implications

Research progress regarding the effect and mechanism of dietary phenolic acids for improving nonalcoholic fatty liver disease via gut microbiota

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