‘Coexisting pituitary adenoma and suprasellar meningioma—a coincidence or causation effect: report of two cases and review of the literature’

Amirjamshidi, Abbas; Mortazavi, Seyed Abolghasem; Shirani, Mohamad; Saeedinia, Saeed; Hanif, Hamed

doi:10.1093/jscr/rjx039

Cited by 21 publications

(30 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In our literature search we found a total of 49 patients with both a meningioma and a pituitary tumour without a history of irradiation. A preference for parasellar localization was found with 22 cases, [4][5][6]10,13,14,16,22,[25][26][27]29,31,[33][34][35][36][38][39][40] of which in 13 cases the tumours were contigious. 6,10,14,22,26,27,31,33,35,[38][39][40] In only three a distinction had been made between the tumours preoperatively.…”

Section: Discussionmentioning

confidence: 99%

“…34 In literature we indeed see a higher proportion of GH-producing adenomas with concomitant meningioma (30.6%). 4,5,[9][10][11]17,20,21,24,29,30,32,35,40 The mechanism through which the GH-adenomas would possibly influence the meningiomas is unclear, but 75% of meningiomas do express GH and IGF-I receptors. 41 Until now no overlapping genetic factors have been discovered in pituitary adenomas and meningiomas.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Unexpected concomitant pituitary adenoma and suprasellar meningioma: a case report and review of the literature

Vries

Lobatto

Najafabadi

et al. 2019

British Journal of Neurosurgery

View full text Add to dashboard Cite

We report a case of a 75-year-old patient with hypopituitarism, bitemporal visual field deficits and a parasellar mass on pituitary MRI. During surgery, suspicion was raised that a non-functioning pituitary adenoma was accompanied by an abutting diaphragm sellae meningioma, which was confirmed at pathological examination. In retrospect, the initial MRI suggested two separate tumours on the basis of differing densities but this distinction was not seen on the last preoperative MRI.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Unexpected concomitant pituitary adenoma and suprasellar meningioma: a case report and review of the literature

Vries

Lobatto

Najafabadi

et al. 2019

British Journal of Neurosurgery

View full text Add to dashboard Cite

show abstract

“…In addition, hyperprolactinemia has been documented in the same patients, suggesting prolactin has a role as a tumor growth factor. Interestingly, several reports have been published on the co‐occurrence of pituitary prolactinoma and other sellar tumors, such as meningioma, gangliocytoma or fibrosarcoma . Transdifferentiation from neoplastic cells of pituitary adenoma has been claimed as a possible pathogenetic mechanism in these cases .…”

Section: Discussionmentioning

confidence: 99%

Pituitary atypical teratoid rhabdoid tumor in a patient with prolactinoma: A unique description

et al. 2017

View full text Add to dashboard Cite

Atypical teratoid rhabdoid tumor (ATRT) is an aggressive tumor of the CNS and characteristically occurs in the pediatric age. In adulthood, ATRT is rare and it is mainly localized in the cerebral hemispheres. Only 16 cases of ATRT have been described in the sellar region up to now. Interestingly, all sellar ATRTs occurred in adult female patients. Herein we report a novel case of sellar ATRT in a patient with previous history of lactotroph adenoma. Similar to other sellar ATRTs, this case occurred in a female adult patient. At histological examination, it was characterized by a small number of rhabdoid cells. In addition, it did not have homozygous deletion of SMARCB1 gene, but it rather showed a frameshift mutation at exon 4 of SMARCB1 which had not been previously found in ATRT. Clinico-pathological and molecular findings observed in this case confirm previous evidence that sellar ATRT seems to be a distinct entity. Association with previous prolactin-secreting pituitary adenoma is discussed.

show abstract

“…Last, two patients with acromegaly were described by Zhao et al and their histopathological reports displayed collision tumors with GH-secreting pituitary adenomas and sella meningiomas [8]. On the other hand, plenty of case reports described various coexistent pituitary adenoma and isolated suprasellar meningioma [33][34][35][36][37][38]. At this point, the difference between "coexistent/concomitant" and "collision" should be underlined.…”

Section: Discussionmentioning

confidence: 99%

Cushing’s disease due to a pituitary adenoma as a component of collision tumor: A case report and review of the literature

et al. 2020

View full text Add to dashboard Cite

Background: The coexistence of two morphologically different tumors attached to each other creates a very rare type of tumor called a collision tumor. Collision tumors containing pituitary adenoma-sellar meningioma have only been described in four cases to date; we discuss a fifth case harboring a collision tumor comprising a pituitary corticotroph adenoma and a sellar meningioma in the same anatomic position. Case presentation: A 34-year-old Caucasian woman presented with menstrual irregularity, severe weakness of the proximal muscles, and 10-15 kg weight gain within a year. Basal plasma cortisol and adrenocorticotrophic hormone levels were 17.7 mg/dL and 58 pg/mL, respectively. Her diurnal cortisol rhythm was impaired (plasma cortisol at 23: 00, 18.2 mg/dL) and after a 48-hour, 2-mg dexamethasone suppression test, plasma cortisol level was 13.6 mg/dL. The results were consistent with a diagnosis of Cushing's syndrome. We then performed a nocturnal 8-mg dexamethasone suppression test and the suppression of cortisol was not greater than 50% (21.4 to 19.3). A pituitary magnetic resonance imaging revealed a tuberculum sellae meningioma arising from within the sellar region. An operation was chosen in order to examine whether the tumor was an adrenocorticotrophic hormone/corticotropinreleasing hormone-secreting lesion or if there were any microadenomas that could be observed during the operation. Via an extended endoscopic endonasal approach the meningioma was resected successfully. Unexpectedly, our patient complained of nausea and vomiting postoperatively. Plasma cortisol was 2.6 mg/dL and orally administered hydrocortisone treatment was initiated immediately. Histopathological examination revealed that the tumor generally consisted of a pituitary corticotroph adenoma infiltrated by meningioma. Our patient maintained hydrocortisone treatment for 11 months. At the latest visit, she had lost 12 kg, and her hypertension, menstrual irregularity, and weakness of the proximal muscles had disappeared. Her mental and physical wellbeing were restored.

show abstract

‘Coexisting pituitary adenoma and suprasellar meningioma—a coincidence or causation effect: report of two cases and review of the literature’

Cited by 21 publications

References 8 publications

Unexpected concomitant pituitary adenoma and suprasellar meningioma: a case report and review of the literature

Unexpected concomitant pituitary adenoma and suprasellar meningioma: a case report and review of the literature

Pituitary atypical teratoid rhabdoid tumor in a patient with prolactinoma: A unique description

Cushing’s disease due to a pituitary adenoma as a component of collision tumor: A case report and review of the literature

Contact Info

Product

Resources

About