Coding region mitochondrial DNA SNPs: Targeting East Asian and Native American haplogroups

Álvarez-Iglesias, Vanesa; Jaime, Juan Carlos; Carracedo, Ángel; Salas, Antonio

doi:10.1016/j.fsigen.2006.09.001

Cited by 80 publications

(89 citation statements)

References 57 publications

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“…In contrast, the basal HVS-I haplotype of D1 (T16362C T16325C) was not detected in our sample. However, we found 11 identical matches of the most common D1 haplotype C16223T C16242T T16311C T16325C T16362C, ten of them in other Argentinean populations: four matches in the Mapuches (Ginther et al 1993) and the rest in the Pilagá and Wichí (Cabana et al 2006) and in the Coyas (Á lvarez-Iglesias et al 2007). Two other matches were also observed in the Genographic database (https://www3.nationalgeographic.com/ genographic/resources.html).…”

Section: Phylogeography Of Mtdna Hvs-i Profilessupporting

confidence: 51%

“…Polymerase chain reaction (PCR) amplification was performed with GeneAmp 9700 thermocyclers, and sequencing analysis was performed as previously described (Á lvarez-Iglesias et al 2007). All samples were additionally genotyped for a set of ten SNPs following (Quintáns et al 2004).…”

Section: Pcr Amplification and Sequencingmentioning

confidence: 99%

“…Five out of nine of the A2 haplotypes match with the basal A2 European and Native American samples plus the one from Córdoba analyzed in this study, whereas the nested small PCA plot includes three additional sub-Saharan African samples. References for population samples are as follows: a Africa (green dots): Mozambique (Salas et al 2002), Angola (Plaza et al 2004), Cabinda (Beleza et al 2005); b Europe (blue dots): Italy (Bini et al 2003), Galicia from Spain (Salas et al 1998), and Germany (Lutz et al 1998); and c America (red dots): Mexico (Green et al 2000), Mapuche from Chile (Moraga et al 2000), Guarani Kaiowá from Brazil (Marrero et al 2007), Coya (Á lvarez-Iglesias et al 2007), Toba and Wichí from Argentina (Cabana et al 2006), Navajo (Monson et al 2002), Ayoreo from Bolivia and Paraguay (Dornelles et al 2004), Ngobe from Panamá (Kolman et al 1995), Córdoba (this study) …”

Section: Phylogeography Of Mtdna Hvs-i Profilesmentioning

confidence: 99%

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Gender bias in the multiethnic genetic composition of central Argentina

et al. 2008

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Section: Phylogeography Of Mtdna Hvs-i Profilessupporting

confidence: 51%

Section: Pcr Amplification and Sequencingmentioning

confidence: 99%

Section: Phylogeography Of Mtdna Hvs-i Profilesmentioning

confidence: 99%

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Gender bias in the multiethnic genetic composition of central Argentina

et al. 2008

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“…To better evaluate the geographical distribution of the novel haplogroups, we surveyed published and unpublished CR data from a wide range of populations (Ginther et al 1993;Horai et al 1993;Alves-Silva et al 2000;Moraga et al 2000;Lalueza-Fox et al 2001;García-Bour et al 2004;Tajima et al 2004;Cabana et al 2006;Á lvarez-Iglesias et al 2007;Tamm et al 2007;Carvalho et al 2008;Salas et al 2008;Bobillo et al 2010;Catelli et al 2011;Gayà-Vidal et al 2011;Prieto et al 2011;Sans et al 2011;MC Bobillo, unpubl.). This allowed the identification of 103 putative D1g and D1j mtDNAs (Supplemental Table S3).…”

Section: Phylogeographic Patterns Of D1g and D1jmentioning

confidence: 99%

Rapid coastal spread of First Americans: Novel insights from South America's Southern Cone mitochondrial genomes

Bodner¹,

Perego²,

Huber³

et al. 2012

Genome Res.

167

169

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It is now widely agreed that the Native American founders originated from a Beringian source population ∼15–18 thousand years ago (kya) and rapidly populated all of the New World, probably mainly following the Pacific coastal route. However, details about the migration into the Americas and the routes pursued on the continent still remain unresolved, despite numerous genetic, archaeological, and linguistic investigations. To examine the pioneering peopling phase of the South American continent, we screened literature and mtDNA databases and identified two novel mitochondrial DNA (mtDNA) clades, here named D1g and D1j, within the pan-American haplogroup D1. They both show overall rare occurrences but local high frequencies, and are essentially restricted to populations from the Southern Cone of South America (Chile and Argentina). We selected and completely sequenced 43 D1g and D1j mtDNA genomes applying highest quality standards. Molecular and phylogeographic analyses revealed extensive variation within each of the two clades and possibly distinct dispersal patterns. Their age estimates agree with the dating of the earliest archaeological sites in South America and indicate that the Paleo-Indian spread along the entire longitude of the American double continent might have taken even <2000 yr. This study confirms that major sampling and sequencing efforts are mandatory for uncovering all of the most basal variation in the Native American mtDNA haplogroups and for clarification of Paleo-Indian migrations, by targeting, if possible, both the general mixed population of national states and autochthonous Native American groups, especially in South America.

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“…We have used the minisequencing technique for screening a total of 258 samples, 10 all for a set of 24 mtDNA SNPs that allow to classify mtDNA sequences into major European haplogroups plus those that are more likely to be of Near East origin (Supplementary Table S1). Those mtDNAs with a SNP profile compatible with a typical Near Eastern haplogroups, that is, HV lineages that are non-H and non-HV0, R0a, U7 and U3, were further sequenced for the first hypervariable segment (HVS-I); only a small fraction of them (B10 of the total sample size) were finally confirmed to belong to the mentioned haplogroups.…”

Section: Genotyping Of Mtdna Snpsmentioning

confidence: 99%