Cochrane in context: Inhaled corticosteroids in children with persistent asthma: effects on growth and dose–response effects on growth

Zhang, Linjie; Pruteanu, Aniela I.; Prietsch, Sílvio O. M.; Chauhan, Bhupendrasinh F; Ducharme, Francine M

doi:10.1002/ebch.1984

Cited by 14 publications

(10 citation statements)

References 12 publications

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“…Asthmatic children when treated with low-dose ICS attain normal adult height but at a later age (Evidence A). [ 321 322 ] Any potential adverse effects of ICS need to be weighed against the well-established benefit to control persistent asthma. More details of the use of ICS in children is available in Appendix 2 There are insufficient data to recommend short courses of high-dose ICS in children with mild intermittent asthma exacerbations (Evidence B).…”

Section: Methodsmentioning

confidence: 99%

The Saudi Initiative for Asthma - 2016 update: Guidelines for the diagnosis and management of asthma in adults and children

et al. 2016

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This is an updated guideline for the diagnosis and management of asthma, developed by the Saudi Initiative for Asthma (SINA) group, a subsidiary of the Saudi Thoracic Society. The main objective of SINA is to have guidelines that are up to date, simple to understand and easy to use by nonasthma specialists, including primary care and general practice physicians. SINA approach is mainly based on symptom control and assessment of risk as it is the ultimate goal of treatment. The new SINA guidelines include updates of acute and chronic asthma management, with more emphasis on the use of asthma control in the management of asthma in adults and children, inclusion of a new medication appendix, and keeping consistency on the management at different age groups. The section on asthma in children is rewritten and expanded where the approach is stratified based on the age. The guidelines are constructed based on the available evidence, local literature, and the current situation in Saudi Arabia. There is also an emphasis on patient–doctor partnership in the management that also includes a self-management plan.

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Section: Methodsmentioning

confidence: 99%

The Saudi Initiative for Asthma - 2016 update: Guidelines for the diagnosis and management of asthma in adults and children

et al. 2016

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“…However, asthmatic children when treated with low-dose ICS attain normal adult height but at a later age (Evidence A). [329330] Any potential adverse effects of ICS need to be weighed against the well-established benefit to control persistent asthma. More details of the use of ICS in children are available in Appendix 1There are insufficient data to recommend short courses of high-dose ICS in children with mild intermittent asthma attacks (Evidence B).…”

Section: Management Of Asthma In Childrenmentioning

confidence: 99%

The Saudi Initiative for Asthma - 2019 Update: Guidelines for the diagnosis and management of asthma in adults and children

et al. 2019

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This is the fourth version of the updated guidelines for the diagnosis and management of asthma, developed by the Saudi Initiative for Asthma (SINA) group, a subsidiary of the Saudi Thoracic Society. The main objective of the SINA is to have guidelines that are up to date, simple to understand, and easy to use by healthcare workers dealing with asthma patients. To facilitate achieving the goals of asthma management, the SINA panel approach is mainly based on the assessment of symptom control and risk for both adults and children. The approach to asthma management is now more aligned for different age groups. The guidelines have focused more on personalized approaches reflecting better understanding of disease heterogeneity with integration of recommendations related to biologic agents, evidence-based updates on treatment, and role of immunotherapy in management. The medication appendix has also been updated with the addition of recent evidence, new indications for existing medication, and new medications. The guidelines are constructed based on the available evidence, local literature, and current situation at national and regional levels. There is also an emphasis on patient–doctor partnership in the management that also includes a self-management plan.

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“…The inhibitory effect on growth has been shown to be dose‐dependent and seems to be related to the suppression of bone formation and inhibition at various levels of the growth hypothalamic‐pituitary axis and adrenal function . It has also been evidenced that the effect of ICs on linear growth is associated more strongly with the IC molecule than with the absolute dose . IC molecules have a different therapeutic index, being related to receptor affinity, pulmonary, and oral bioavailability , and they differ even when they are used at the same dose .…”

mentioning

confidence: 99%

“…It has also been evidenced that the effect of ICs on linear growth is associated more strongly with the IC molecule than with the absolute dose . IC molecules have a different therapeutic index, being related to receptor affinity, pulmonary, and oral bioavailability , and they differ even when they are used at the same dose .…”

mentioning

confidence: 99%

Influence of inhaled corticosteroids on pubertal growth and final height in asthmatic children

Leonibus

Attanasi

Roze

et al. 2016

Pediatric Allergy Immunology

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Cochrane in context: Inhaled corticosteroids in children with persistent asthma: effects on growth and dose–response effects on growth

Cited by 14 publications

References 12 publications

The Saudi Initiative for Asthma - 2016 update: Guidelines for the diagnosis and management of asthma in adults and children

The Saudi Initiative for Asthma - 2016 update: Guidelines for the diagnosis and management of asthma in adults and children

The Saudi Initiative for Asthma - 2019 Update: Guidelines for the diagnosis and management of asthma in adults and children

Influence of inhaled corticosteroids on pubertal growth and final height in asthmatic children

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