Cocaine convulsions in a brast-feeding baby

Chaney, Nancy E.; Franke, Jenny; Wadlington, William B.

doi:10.1016/s0022-3476(88)80139-2

Cited by 68 publications

(12 citation statements)

References 4 publications

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“…The infant had seizures 3 hours later and required ventilator assistance for 24 hours. 51 These reports suggest that cocaine is transferred to human milk and it is understandable because of the high lipid solubility, pKa of 8.6 (weak base), and high bioavailability (80-90%) of the drug allowing it to readily cross into maternal plasma and into the breast milk. 25,52 Alcohol (ethanol) has a very low molecular weight, no plasma protein binding, and is a strong base ( Table 1).…”

Section: Marijuana/cocaine/alcohol/heroinmentioning

confidence: 99%

Breastfeeding and Substance Abuse

DʼApolito

2013

Clinical Obstetrics &Amp; Gynecology

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Breastfeeding is the recommended feeding method for infants. The decision to allow women to breastfeed while consuming alcohol and other drugs postpartum presents a problem for the health care provider. This article discusses the biochemical properties of various drugs as they relate to breastfeeding. Women in a methadone treatment program should be allowed to breast feed; however, more research is needed to determine the efficacy of breastfeeding when women are receiving buprenorphine. Breastfeeding should not be recommended in women who abuse heroin recreationally until more information is known about the actual amount of morphine present in the breast milk.

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Section: Marijuana/cocaine/alcohol/heroinmentioning

confidence: 99%

Breastfeeding and Substance Abuse

DʼApolito

2013

Clinical Obstetrics &Amp; Gynecology

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“…There have been reports documenting neonatal effects due to breast milk exposure; therefore, the decision to breastfeed should be made on an individual basis after discussing the potential risks and benefits [146,147,149,150]. Breastfeeding may be delayed after maternal use of any of these agents and any neonatal exposure to any fumes in the environment.…”

Section: Breastfeedingmentioning

confidence: 99%

Substance use in pregnancy

Wong¹,

Ordean²,

Kahan³

2011

Intl J Gynecology & Obste

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“…An example exists where cocaine was applied directly to the breast for pain control and the nursing infant experienced apnea and seizures. 88 The area should be cleansed thoroughly before the infant feeds, and the safety of each agent should be assessed before application.…”

Section: Topical Preparationsmentioning

confidence: 99%

Medications and Breast-Feeding: A Guide for Pharmacists, Pharmacy Technicians, and other Healthcare Professionals Part II

Nice

DeEugenio

DiMino

et al. 2004

Journal of Pharmacy Technology

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The following discussion of medication categories, which includes drugs used in cardiology and general practice, will help pharmacists and other healthcare professionals understand which drugs are the optimal choices within specific categories for breast-feeding mothers to take while minimizing the impact on in-fants. Ambulatory care medications and analgesics and anesthetics were discussed in Part I of this 3-part series. 1 Objective: To provide a guide for practicing pharmacists, pharmacy technicians, and other healthcare professionals so that they are able to counsel and advise breast-feeding mothers and fellow healthcare professionals on the safety and use of common cardiology and general medications during breast-feeding.Data Sources: Primary texts used by the breast-feeding community (Medications and Mothers' Milk, Drugs in Pregnancy and Lactation, Drugs and Human Lactation) were searched, as well as Micromedex, MEDLINE, PubMed, EMBASE, and EMBASE2 (1984( -February 2004. Study Selection/Data Extraction:Multiple sources were used wherever available to validate the data, and primary articles were used to verify all tertiary source information. Search terms included breast-feeding, lactation, nursing, and medications, as well as specific drug names.Data Synthesis: Concerns regarding medication use during breast-feeding have caused mothers to either discontinue nursing or not take necessary medications. Complete avoidance of medications or cessation of breast-feeding is often unnecessary. Although there are drugs that can be harmful to nursing infants, breast milk concentrations of most drugs are insufficient to cause any harm. Conclusions:Having objective and reliable information on medications enables pharmacists, pharmacy technicians, healthcare providers, and mothers to make educated decisions regarding drug therapy and breast-feeding.

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Cocaine convulsions in a brast-feeding baby

Cited by 68 publications

References 4 publications

Breastfeeding and Substance Abuse

Breastfeeding and Substance Abuse

Substance use in pregnancy

Medications and Breast-Feeding: A Guide for Pharmacists, Pharmacy Technicians, and other Healthcare Professionals Part II

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