Cobalt-60 Treatment of Choroidal Hemangiomas

Zografos, Léonidas; Bercher, L.; Chamot, Line; Gailloud, C; Raimondi, S.; Egger, Emmanuel

doi:10.1016/s0002-9394(14)70584-7

Cited by 109 publications

(49 citation statements)

References 11 publications

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“…Zografos et al 160 treated 54 patients with choroidal haemangiomas (48 circumscribed, 6 diffuse) using proton beam irradiation and found a resolution of the retinal detachment in all cases. The same group had previously reported the results of treatment of these lesions with Cobalt-60 brachytherapy 161 and found that in all 41 cases there was reattachment of the retina and replacement of the tumour by a flat scar. Madreperla et al 162 in a retrospective study of the treatment of circumscribed choroidal haemangiomas by photocoagulation, brachytherapy or external irradiation concluded that both forms of irradiation were an effective alternative to photocoagulation.…”

Section: Primary Choroidal Tumoursmentioning

confidence: 81%

Things that go bump in the light. The differential diagnosis of posterior uveal melanomas

Rennie

2002

Eye

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Section: Primary Choroidal Tumoursmentioning

confidence: 81%

Things that go bump in the light. The differential diagnosis of posterior uveal melanomas

Rennie

2002

Eye

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“…Complications included pigment migration into the treated area, subretinal fibrosis and an areolar atrophic scar. [71] Subretinal fluid was resolved in all patients treated by Shields et al and visual acuity improved or became stable in 53 % of cases. [1] The disadvantage of plaque brachytherapy is the necessity for two surgeries for plaque placement and removal.…”

Section: Plaque Brachytherapymentioning

confidence: 84%

“…[68] Brachytherapy with palladium-103, cobalt-60, ruthenium-106, and iodine-125 have all been used for treatment of circumscribed choroidal hemangioma. [1,[68][69][70][71][72] Tumor regression and resolution of subretinal fluid was noted in all patients treated with iodine-125 plaque, and signs of radiation retinopathy were noted in 38% of subjects. [70] Zografos et al reported the largest series of 39 patients with circumscribed choroidal hemangioma treated with cobalt-60 plaque brachytherapy who showed 100% retinal reattachment.…”

Section: Plaque Brachytherapymentioning

confidence: 99%

Circumscribed choroidal hemangioma

Mashayekhi

Shields

2003

Current Opinion in Ophthalmology

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Circumscribed choroidal hemangiomas are benign vascular hamartomas without systemic associations. Generally, they are orange-red elevated masses, which are found posterior to the equator. Lesions are usually solitary and unilateral. Overlying subretinal fluid, serous retinal detachment and cystoid macular edema are common findings. Intravenous fluorescein angiography, indocyanine green angiography, ultrasonography, optical coherence tomography and enhanced depth imaging are helpful ancillary tests for diagnosis of circumscribed choroidal hemangiomas. Asymptomatic circumscribed choroidal hemangiomas do not require treatment. For symptomatic lesions with exudative retinal detachment or cystoid macular edema, photodynamic therapy has emerged as the treatment of choice with high rates of tumor regression, subretinal fluid resorption and minimal complications. Lens-sparing external beam radiotherapy, plaque brachytherapy, proton beam therapy, stereotactic radiosurgery, transpupillary thermotherapy, laser photocoagulation and anti-VEGF injections are other treatment modalities.

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“…If the patient is asymptomatic no treatment is indicated. If the visual acuity drops, usually occurring in the third or fourth decade, several therapies have been advocated, such as argon laser treatment [7,8,18,30], radiation (external beam, photon irradiation, brachytherapy) [12,13,14,19,21,32,41,42], and hyperthermia (microwave thermo therapy, transpupillary thermotherapy) [9,10,11,16,25,28]. In 2000, Barbazetto and Schmidt-Erfurth used photodynamic therapy with verteporfin in two patients [6].…”

Section: Introductionmentioning

confidence: 99%