Coagulase-negative Staphylococcus Endophthalmitis After Cataract Surgery With Intraocular Vancomycin

Intracameral cefazolin as prophylaxis against endophthalmitis in cataract surgery

“…15,16 In fact, 1 report documented the development of coagulasenegative Staphylococcus endophthalmitis sensitive to vancomycin after cataract extraction despite the fact that vancomycin was used in the infusion fluid. 17 Because all prophylactic measures were used, we decided to add 1 mg of cefazoline in the capsular bag at the end of cataract surgery to our prophylactic program.…”

Preoperative Disinfection of the Conjunctival Sac in Cataract Surgery

“…Recently recommended preparations to reduce the risk of postoperative endophthalmitis in cataract surgery in clude antibiotics in the intraocular irrigating solution [ 13,14] and the routine use of povidone-iodine as a preopera- five disinfectant [15][16][17], Controversy remains over the use of antibiotics especially vancomycin, because of prob able adverse effects, the induction of vancomycin-resis tant bacteria, and financial limitations [18,19], To define the most appropriate preoperative preparation of the external eye against endophthalmitis, we evaluated the species and incidence of bacteria in the conjunctiva and lids which may gain access into the eye during cataract surgery [2][3][4][5][6][7][8].…”

Aderência bacteriana in vitro a lentes intra-oculares de polimetilmetacrilato e de silicone

“…Diferentes tipos de bactérias podem causar endoftalmite sendo estafilococos coagulase-negativos, mais especificamente S. epidermidis, os agentes mais comumente isolados (6,(10)(11)(12)(13) . Sabe-se que S. epidermidis tem habilidade de se aderir e proliferar em superfícies de polímeros, especialmente lentes intra-oculares, secretando uma matriz extracelular viscosa (biofilme) que o protege contra antibióticos, bem como dos mecanismos de defesa do hospedeiro (10,(14)(15)(16) . A adesão bacteriana a lentes intra-oculares e a produção de biofilme parecem estar associadas à sua carga eletrostática superficial e às cepas produtoras de cápsula (12,17) , variando de intensidade conforme o tipo de lente testado (11,18) .…”