CO₂-laser therapy for carcinoma of the larynx

Abstract

A retrospective study was undertaken to assess the outcome of 19 consecutive patients, who underwent endolaryngeal resection with a CO2-laser for laryngeal carcinomas. Sixteen of these patients had recurrences after primary curative radiotherapy. Seventeen of the patients had a curative operation carried out. So far, four CO2-laser treatment failures have been observed (median observation time 35 months). None of the patients needed tracheostomy in connection with the operation. Voice quality was in all cases acceptable.It is recommended, that small recurrences (after radiotherapy of laryngeal squamous cell carcinomas)should be considered for a partial laryngectomy with the aid of a laser.

Partial laryngectomy for recurrent glottic carcinoma after radiotherapy

“…Outzen and Illum 16 reported similar results. After salvage procedures, a 5-year cure-rate of 98% was achieved.…”

Salvage Transoral Laser Microsurgery for Radiorecurrent Laryngeal Cancer: Indications, Limits, and Outcomes

“…The series of Puxeddu et al [15] is a two-center retrospective case series, with results of one included center updated in a later publication by Piazza et al [16], which, in turn, was updated by Del Bon et al [17]. Most authors reported on series of rT1 to rT2 glottic cancer, while some authors also included more advanced glottic cases (rT3 or even rT4) [11••, 18–21] or supraglottic recurrences [14, 18, 20–22]. …”

Salvage Endoscopic Angiolytic KTP Laser Treatment of Early Glottic Cancer after Failed Radiotherapy

“…Prior investigations have found that endoscopic carbon dioxide (CO2) laser and transcervical open partial laryngectomy procedures are a reasonable strategy in selected cases, providing similar survival rates for patients who otherwise would have total laryngectomy. 2,[5][6][7][8][9][10][11][12][13][14] This is the first report to describe use of the angiolytic 532-nm KTP laser in a salvage strategy for recurrent glottic carcinoma after radiotherapy, as opposed to the typical choice of a CO2 laser. Motamed et al 2 reviewed all Medline database articles from 1985 to 2005 on salvage conservation laryngeal surgery that had a sample size of greater than 10 and a follow-up of greater than 24 months.…”