The HEIs face challenges that require new teaching practices adjusted to the new realities and demands of the market. Companies and organizations seek transversal competences to solve immediate problems and project future scenarios. Co-creation between higher education institutions (HEIs) and companies make it possible to prepare students for the increasingly demanding and innovative labor market, particularly in the tourism and accommodation industry. This chapter presents contributions to applying innovative and interdisciplinary methodologies in the pedagogical practices of tourism and accommodation teaching. A teaching-learning model based on co-creation methods is proposed and illustrated with a case study developed in partnership with a regional tourist enterprise in Portugal. The chapter concludes with an analysis of the co-creation model's impact and an analysis of pedagogical tools for developing new and innovative accommodation products and services that are essential for differentiation and positioning in marketing strategies.