CNS Tuberculosis and Other Mycobacterial Infections

García-Moncó, Juan Carlos; Rodriguez-Sainz, Aida

doi:10.1007/978-1-4471-6401-2_8

Cited by 4 publications

(4 citation statements)

References 87 publications

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“…The neurological manifestations associated with chikungunya are uncommon and variable. Various manifestations like meningoencephalitis, myelitis, Guillain–Barre syndrome, cranial nerve palsies, encephalomyeloradiculitis, and neuropathy have been reported [ 1 , 2 ].…”

Section: Discussionmentioning

confidence: 99%

“…Alphaviruses having single-stranded RNA genome belong to Togaviridae family of viruses and are divided into arthritogenic viruses (old world) and encephalitogenic viruses (new world) including equine encephalitis viruses. It is transmitted by the mosquitoes of Aedes genus amongst which Aedes aegypti being the principal vector in earlier times now viral host range includes A. albopictus as well [ 1 ].…”

Section: Introductionmentioning

confidence: 99%

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A Case Report on Chikungunya Virus-Associated Encephalomyelitis

Khatri

Shah

Roy

et al. 2018

Case Reports in Infectious Diseases

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Chikungunya is a rerising alphavirus infection that has resulted from enhanced vector competence. Alphaviruses are divided into arthritogenic viruses (old world) and encephalitogenic viruses (new world) including equine encephalitis viruses. Chikungunya is a dengue-like illness characterized by acute febrile polyarthralgia, arthritis, malaise, body ache, rash, headache, and nausea. The illness is self-limiting. The neurological manifestations are uncommon and incorporate meningoencephalitis, myelitis, Guillain–Barre syndrome, cranial nerve palsies, myelopathy, and neuropathy; MRI abnormalities in patients with encephalopathy from India have been reported in the form of multiple punctuate white matter lesions that are more prominent on diffusion-weighted MRI than on T2 or T1. Here, we present an intriguing case of chikungunya encephalomyelitis who presented to our tertiary care hospital with quadriparesis and urinary retention. He was treated with 5 doses of intravenous immunoglobulin along with supportive care with which he showed partial recovery.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A Case Report on Chikungunya Virus-Associated Encephalomyelitis

Khatri

Shah

Roy

et al. 2018

Case Reports in Infectious Diseases

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“…Polymerase chain reaction (PCR) and immunohistochemistry (IHC) are increasingly useful for confirmation [10]. Diagnosis of tuberculosis made by culture takes long time of involved tissues (growing the bacteria), a process that takes at least eight weeks and therapy requires a prolonged, multidrug regimen [15,20]. An estimated 60 million lives were saved through TB diagnosis and treatment between 2000 and 2019.…”

Section: Diagnosis Of Swine Tuberculosismentioning

confidence: 99%

Tuberculosis in Swine: Prevalence and Basic Diagnostic Approach

Shiferaw¹

2021

Prog Med Sci

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“…Delay in diagnosis and so in the start of effective treatment results in poor prognosis and sequalae in up to 25% of cases. 4 Prompt diagnosis is critical for initiating appropriate therapy and facilitating measures to prevent dissemination of this highly contagious disease. The prevalence of TB meningitis remains largely underestimated because clinical manifestations are nonspecific in early stages of the disease and bacteriologic confirmation is available only for a small proportion of patients.…”

Section: Introductionmentioning

confidence: 99%

Diagnosis of tuberculosis meningitis by using Trc4 and Is6110 primers in Bangladesh

Sattar

Setu

Firoz

et al. 2019

JMEN

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Meningitis caused by Mycobacterium tuberculosis remains an important cause of morbidity and mortality worldwide, and presents particular challenges in terms of diagnosis and management. The prevalence of TB meningitis remains largely underestimated due to nonspecific clinical manifestation. At early stages diagnosis is largely based on microscopy and culture which are often less sensitive and time consuming. This study was aimed to evaluate the diagnostic potentials of urinary polymerase chain reaction (PCR) by using TRC4 and IS6110 primers. Further the results were also compared by culture on Lowenstein-Jensen (LJ) media and AFB smear by Zeihl-Nelson (ZN) staining. A total of 20 CSF samples were studied from clinically suspected cases of tubercular meningitis. All the samples were processed for conventional ZN staining, TB culture on LJ media and TB-PCR by IS6110 and TRC4 primers by standard protocols. Of the total 20 samples, 12 cases were diagnostically positive TB meningitis samples among which bacteriological test were positive in only 1(8.33%) cases. PCR assay detected MTb in 10(83.33%) patients by TRC4 primers and in 8 (66.67%) patients by IS6110 primers. Since some strains of MTB may lack the IS6110 element in their genome using TRC4 primer instead of IS6110 is superior in diagnosing tubercular meningitis by PCR assay.Citation: Sattar ANI, Setu SK, Firoz TH, et al. Diagnosis of tuberculosis meningitis by using Trc4 and Is611o primers in Bangladesh.

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CNS Tuberculosis and Other Mycobacterial Infections

Cited by 4 publications

References 87 publications

A Case Report on Chikungunya Virus-Associated Encephalomyelitis

A Case Report on Chikungunya Virus-Associated Encephalomyelitis

Tuberculosis in Swine: Prevalence and Basic Diagnostic Approach

Diagnosis of tuberculosis meningitis by using Trc4 and Is6110 primers in Bangladesh

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