CMOS Multi-Frequency Lock-in Sensor for Impedance Spectroscopy in Microbiology Applications

Hosseini, S. Nazila; Lazarjan, Vahid Khojasteh; Akram, M. Makhdoumi; Gosselin, B

doi:10.1109/newcas52662.2022.9842207

Cited by 3 publications

(1 citation statement)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Dielectrophoresis can be used to manipulate the movement of bacteria and other particles using electric fields 22 (Figure 2a), which can help to improve the sensitivity and specificity of impedance measurements, and with a results provided within 1hrs. here are also many other potential applications of impedance spectroscopy in microbiology and biomedicine, such as for monitoring cell viability, detecting bacterial infections, and studying the effects of drugs and other compounds on cells and tissues [23][24][25][26] . Also, Impedance spectroscopy enables the detection of significant parameters such as the bacteriostatic or bactericidal characteristics of novel and existing antimicrobial compounds 27 and whole cell detection of vancomycin susceptibility 28 .…”

Section: Electrochemical Phenotypic Antimicrobial Susceptibility Testingmentioning

confidence: 99%

Revolutionizing Phenotypic Antimicrobial Susceptibility Testing: Lightning-Fast Techniques Based on Cutting-Edge Electrochemistry

R¹

2023

Preprint

View full text Add to dashboard Cite

Due to the ongoing concern for the development of rapid and accurate antimicrobial susceptibility testing (AST) methods in the field of clinical microbiology, several novel AST systems have been developed to replace the traditional gold standard AST techniques, which are time-consuming and can lead to delayed susceptibility guided therapy outcomes. In this review, the focus is on the phenotypic assays based on electrochemistry that are used to determine bacterial susceptibility towards antibiotics. Electrochemical techniques have gained significant interest in the field of AST due to their rapidity, sensitivity, and specificity, although it is important to note that some of these methods may have limitations regarding the specific classes of antibiotics and bacteria that they can be applied to, which researchers can address by fine-tuning the techniques or incorporating additional controls. By offering significant advantages over traditional AST methods in terms of rapidity and accuracy, electrochemical phenotypic assays could lead to improved patient outcomes.

show abstract