The article describes typology of regions of AIRR based on factor and cluster analysis. The main purpose of typology in this study is seeking for opportunities to transform interregional differentiation from problem into an additional source of development of regions with different complementary models of innovation development. It highlights 4 main and 2 additional types (subtypes) of regions of AIRR: Type 1 "Industrial innovation-active regions" (Subtype 1 "regions with developed medium-technological industries" and Subtype 2 "regions with developed high-technological industries"), Type 2 "Industrial regions providing demand for innovations ("market"), Type 3 "Regions with developed scientific-educational complex", Type 4 "Mixed (catching-up)". Peculiarities of different types of regions allow each region achieving an efficient innovative activity through complementarity of resources if each region fulfills its role, defined by type of innovative development. It makes actual the problem of development of mechanism of interregional innovation policy as one of the area of development of a synergistic approach in the state innovative policy.