“…In BALB/c mice, it has been demonstrated that the spleen serves several important roles during irradiation, including being a site for the development of protective and pathological immune responses following irradiation (Kraal et al, 1989;Weiss, 1989). Some reports also concluded that the level of protein in spleen and splenocyte apoptotic bodies had significant increases after dose of 5.0 or 7.5 Gy (Amer, 1993;Klokov et al, 2003).…”