Clozapine and Aripiprazole-Induced Stuttering: A Case Report of Turner Syndrome with Schizophrenia

Clozapine-induced Weight Loss and Stuttering in a Patient with Schizophrenia

“…This study also observed that dopamine activity in stutterers was found to be 50%–200% higher than that in persons who were not stutterers. [ 4 ]…”

“…Stuttering happens due to rapid titration of dose and higher dose and presence of multiple drugs leading to drug interactions. [ 4 6 ]…”

“…[3] Second, stuttering is defined as a disruption in the normal fluency and pattern of speech, in which a person tends to repeat sounds and syllables. [4] Stuttering associated with antipsychotics is rarely encountered in clinical practice. It may occur as a side effect of antipsychotics such as chlorpromazine, trifluoperazine, fluphenazine, olanzapine, risperidone, and rarely clozapine and aripiprazole then selective serotonin reuptake inhibitors and tricyclic antidepressants.…”

“…It may occur as a side effect of antipsychotics such as chlorpromazine, trifluoperazine, fluphenazine, olanzapine, risperidone, and rarely clozapine and aripiprazole then selective serotonin reuptake inhibitors and tricyclic antidepressants. [4][5][6] Here, we are presenting a case where the patient developed weight loss as well as stuttering while undergoing clozapine therapy.…”

“…This study also observed that dopamine activity in stutterers was found to be 50%-200% higher than that in persons who were not stutterers. [4] Stuttering with clozapine has been reported with higher than 600 mg of doses. EEG abnormalities are very common in such cases which often warrant adding to anticonvulsants.…”