Clostridium difficile enteritis in a patient after total proctocolectomy

Peacock, Oliver; Speake, William J.; Shaw, Aidan; Goddard, Andrew

doi:10.1136/bcr.10.2008.1165

Cited by 7 publications

(4 citation statements)

References 15 publications

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“…Veterinary studies were excluded, as were basic science studies and articles focusing on pediatric patients (age <18 years). Per our selection strategy, 77 reported cases were identified in 49 publications and our results are presented in Table 1 [ 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 ].…”

Section: Discussionmentioning

confidence: 99%

Clostridioides Difficile Enteritis: Case Report and Literature Review

et al. 2022

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Background: Clostridioides Difficile is a well-known pathogen causing diarrhea of various degrees of severity through associated infectious colitis. However, there have been reports of infectious enteritis mainly in patients with ileostomy, causing dehydration through high-output volume; Case presentation: We report the case of a 46-year-old male patient, malnourished, who presented with high-output ileostomy following a recent hospitalization where he had suffered an ileo-colic resection with ileal and transverse colon double ostomy, for stricturing Crohn’s disease. Clostridioides Difficile toxin A was identified in the ileal output confirming the diagnosis of acute enteritis. Treatment with oral Vancomycin was initiated with rapid reduction of the ileostomy output volume; Conclusion: We report a case of Clostridioides Difficile enteral infection as a cause for high-output ileostomy, successfully treated with oral Vancomycin. We also review the existing literature data regarding this specific localized infection.

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Section: Discussionmentioning

confidence: 99%

Clostridioides Difficile Enteritis: Case Report and Literature Review

et al. 2022

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“…C difficile can cause pseudomembranous colitis via a toxin‐mediated inflammatory process through production of C difficile toxin A and C difficile toxin B (1). Although believed to be limited to the colon, there is a growing body of evidence from adult studies demonstrating that C difficile can also cause small bowel enteritis, particularly in patients with a history of IBD (2–7). To our knowledge, this is the first reported case of C difficile –positive small bowel enteritis in a pediatric patient with IBD.…”

Section: Discussionmentioning

confidence: 99%

“…In our patient's case, high stool output from her ileostomy and abdominal pain were concerning for either a Crohn's flare or infectious enteritis. On review of the literature, the majority of patients with C difficile –positive small bowel enteritis presented with similar symptoms (Table 1) (2–7). Furthermore, the patients with a history of colectomy and ileostomy frequently presented with high‐volume, watery ileostomy diarrhea and subsequent ileus (8).…”

Section: Discussionmentioning

confidence: 99%

Clostridium difficile Ileitis in Pediatric Inflammatory Bowel Disease

Butler

Torres-Torres

Pahud

et al. 2017

J. pediatr. gastroenterol. nutr.

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“…In the reported cases of post-operative C. difficile, patients underwent bowel manipulation usually involving partial or complete resections of the colon and subsequently were in states of prolonged or permanent bowel discontinuity [8][9][10][11][12][13][14][15][16][17][18][19].…”

Section: Discussionmentioning

confidence: 99%

IsolatedClostridium difficileSmall Bowel Enteritis in the Absence of Predisposing Factors

SchublSebastian

RaymondLoveita

et al. 2016

Surgical Infections Case Reports

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Background: Clostridium difficile colitis is a growing problem as antibiotic use and resistance continues to plague healthcare, yet few articles documenting the occurrence and outcomes of C. difficile small bowel enteritis exist. We believe to have the first reported case of C. difficile enteritis originating in the small bowel, in absence of any previously reported risk factors for this rare infection with high mortality. Case Presentation: A 71-year-old female presenting with bowel obstruction and strangulation was found to have C. difficile enteritis after bowel resection and discontinuity that was found repeatedly to be isolated to the small bowel despite an intact, healthy colon. Conclusion: The possibility of small bowel C. difficile in surgically manipulated small bowel is real, even in the absence of long-term antibiotic use, inflammatory bowel disease, or immunodeficiency and with a normal colon in place. This is an entity not described previously and further expands the potential impact of this ubiquitous bacterium. C lostridium difficile colonization in the large bowel is a common cause of colitis in hospitalized patients after antibiotic exposure. Yet, it rarely colonizes the small bowel and seldom causes active small bowel enteritis. The few reported cases of small bowel C. difficile enteritis are observed in patients that have well-documented histories of inflammatory bowel disease (IBD), prolonged antibiotic use, immunosuppressive therapy, or who have undergone a total or subtotal colectomy. In this article we present a case of C. difficile infection isolated to the small bowel in a patient with no prior history of the risk factors outlined previously.

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Clostridium difficile enteritis in a patient after total proctocolectomy

Cited by 7 publications

References 15 publications

Clostridioides Difficile Enteritis: Case Report and Literature Review

Clostridioides Difficile Enteritis: Case Report and Literature Review

Clostridium difficile Ileitis in Pediatric Inflammatory Bowel Disease

IsolatedClostridium difficileSmall Bowel Enteritis in the Absence of Predisposing Factors

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