Clinicopathological Study of Uterine Lesions in Hysterectomy Specimens

Abstract

Background: Women worldwide suffer from various gynaecological disorders that require hysterectomy as a treatment option. Objectives: Our aim was to conduct a histopathological study of various uterine lesions in hysterectomy specimens and to correlate the findings with clinical indications. Methods: A prospective study was done on 200 hysterectomy specimens. The specimens were fixed in formalin and the tissue was adequately processed. The sections were stained with routine Haematoxylin and Eosin stain. Results: In this study the most common clinical indication for hysterectomy was leiomyoma (57.0%) followed by utero-vaginal prolapse (28.5%). Clinical indication of leiomyoma was confirmed by histopathology in 96.5% cases, whereas that of cervical dysplasia, cervical polyp, squamous cell carcinoma cervix, chronic pelvic inflammatory disease, adenomyosis and endometrial carcinoma was confirmed in 100% cases. Conclusion: The ultimate diagnosis and prognosis depends on the histopathological examination; therefore every operated specimen must be subjected to histopathology.

Histomorphological study of lesions of corpus uteri in hysterectomy specimens: a tertiary care centre study

“…GR et al (47.27%)[5]. The present study showed a mean age of 42.15 years which almost corroborated with the study of Kaur SJ et al[12] where the mean age was 46 years.…”

“…In a descriptive study of 100 hysterectomy specimens conducted by Sarfraz R et al (2011), most common neoplastic lesions were leiomyoma, adenomyosis, endometrial hyperplasia, etc and some of the specimens had more than one lesion in the body of uterus and concluded that coexistence of adenomyosis and leiomyoma were common [2]. [15] and Chaturvedi V et al [16] and Kaur SJ et al [12]. A rare and interesting case (0.22%) of bicornuate uterus with intramural leiomyoma was noted in this study, which correlated with study of Eligar RC et al [17].…”