Clinicopathological study of benign soft tissue neoplasms: Experience at rural based tertiary teaching hospital

Narhire, Vikas; Bagate, Arvind N.; D'Costa, Grace

doi:10.5958/2394-6792.2016.00052.1

Cited by 3 publications

(5 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The head neck region was also the most common site for vascular tumors as described by Rao B.S. et al [10] , Narhire VV et al [21] and Deepak M B et al [17] , similar to our study.…”

Section: Discussionsupporting

confidence: 92%

“…The external and histological findings described by Gabhane S.K. et al [25] and Narhire VV et al [21] of ancient, cellular and conventional schwannomas and S100 positivity used by Vahini G. [6] was compatible with ours. Vahini G [6] , Rao B.S.…”

Section: Discussionsupporting

confidence: 89%

“…------01(0.5%) -by Narhire VV et al [21] , Rao B.S. et al [10] , Kanth et al [26] and Agravat A.H. et al [14] matched our findings.…”

Section: -100supporting

confidence: 87%

“…et al [25] and Rao B.S. et al [10] in their studies described the gross morphologies of neurofibromas while microscopic findings in studies by Narhire VV et al [21] , Chakrabarti P.R. et al [16] and Gabhane S.K.…”

Section: Discussionmentioning

confidence: 99%

“…Chakrabarti P.R. et al [16] and Narhire VV et al [21] described hemangiomas as irregular polypoidal tissues with a brownish cut surface. The microscopic morphologies of capillary, cavernous hemangiomas, hemangioendothelioma and lymphangioma Chakrabarti P.R.…”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

A Retrospective Study of Soft Tissue Tumors - Role of Histomorphology in Diagnosis

Damani¹,

Patil²,

Ansari³

et al. 2020

Ann of Pathol and Lab Med

View full text Add to dashboard Cite

Background: The field of soft tissue tumors is vast and yet to be explored. The diagnosis of these tumors is always challenging for the pathologists. The overlap in the clinical and radiological features makes histopathology very crucial in their identification. Methods: This is a retrospective study of soft tissue tumors over a period of 18 months from January 2014 to June 2015 conducted in the Department of Pathology. The gross specimens were fixed in 10% formalin and the slides were stained by Hematoxylin and Eosin. Immunohistochemistry was performed wherever necessary. Result: A total of 235 soft tissue tumors were studied of which benign cases were 225 (95.75%), intermediate 04 (1.70%) and malignant 06 (2.55%). The tumors had a male preponderance, with majority in the third decade, predominantly occurring in the head neck region. Of a total of eleven categories of soft tissue tumors in our study, the adipocytic category was the most common followed by the nerve sheath and vascular tumors. Conclusion: Molecular diagnosis have started to gain momentum in the field of soft tissue tumors, however histomorphology still remains the gold standard.

show abstract

“…The head neck region was also the most common site for vascular tumors as described by Rao B.S. et al [10] , Narhire VV et al [21] and Deepak M B et al [17] , similar to our study.…”

Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 89%

“…------01(0.5%) -by Narhire VV et al [21] , Rao B.S. et al [10] , Kanth et al [26] and Agravat A.H. et al [14] matched our findings.…”

Section: -100supporting

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

A Retrospective Study of Soft Tissue Tumors - Role of Histomorphology in Diagnosis

Damani¹,

Patil²,

Ansari³

et al. 2020

Ann of Pathol and Lab Med

View full text Add to dashboard Cite

show abstract

Clinico-pathological study of soft tissue tumors

Begum¹,

K²,

K³

et al. 2020

IJPO

View full text Add to dashboard Cite

Soft tissue tumors (STT) are a diverse group of tumors. The prognosis of soft tissue tumors is unpredictable and aggressive if not diagnosed early. A vast majority of STT are benign, having a very high cure rate following surgical excision. Benign tumors vary widely in appearance and behavior. The sub-classification of these benign tumors is essential for prognosis as well as clinical management of patients. Histopathology is considered gold standard in the diagnosis of benign STT. To study the clinicopathological profile of benign STT in terms of incidence, age, sex, site distribution, gross and histopathological features and their correlation with clinical diagnosis.This descriptive study included 249 patients with benign STT whose excision specimens were analyzed in the Department of Pathology over five years from January 2013 to December 2017.Benign STT constituted 14.7% of all types of neoplasms in the present study. Among STT, benign tumors formed the majority (92.2%). Adipocytic tumors formed the most common histologic group. Benign STT showed a slight male preponderance with peak incidence in the fourth decade. The most common site of occurrence was the trunk followed by head and neck.With this study, we were able to reassess the clinicopathological profile of benign soft tissue STT and their different types with respect to age, sex, and site distribution.

show abstract

Histopathological Study of Soft Tissue Tumours and Correlation of Histologic Grade of Sarcomas With Proliferative Marker Ki-67

Raasi¹,

Kumari

2022

IJAR

View full text Add to dashboard Cite

INTRODUCTION:Soft tissue tumours have diagnostic and therapeutic challenge due to a wide variety of histomorphological patterns. Soft tissue sarcomas are relatively infrequent and constitute less than 1 % of all malignant neoplasms. Immunohistochemical evaluation of Ki-67 is a rapid prognostic tool to assess the cellular proliferation better than mitotic index. METHODS: A prospective study was conducted with a total of 100 cases of soft tissue tumors to analyze the frequency and histomorphology. Soft tissue sarcomas were graded by FNCLCC grading system and were subjected to Ki-67 evaluation. Spearman's Rho and Pearman's correlation coefcients were calculated to determine the correlation between the histologic grade and Ki-67 index. RESULTS: Soft tissue tumours constituted only about 1.3% of all neoplasms. Benign tumours (50%) outnumbered intermediate (11%) and malignant soft tissue tumours (39%). Soft tissue tumours were more common in males (52%) than females (48%) and frequently observed in the sixth decade. The sites of predilection were upper extremities for benign tumours and lower extremities for malignant tumours. Most common benign soft tissue tumour was Neurobroma (19%) followed by Schwannoma (14%). Undifferentiated pleomorphic sarcomas were the most common malignant soft tissue tumour (28%). In FNCLCC grading, most of the sarcomas were grade III (42%). Ki-67 index was low in grade I sarcomas, variable in grade II sarcomas and high in grade III sarcomas. Spearman's rho and Pearman's correlation R values were 0.77 and 0.75 respectively and p value is less than 0.05. CONCLUSION: There is positive correlation between the histologic grade and Ki-67 proliferative index in soft tissue sarcomas. Ki-67 index can be used as an independent prognostic factor to predict the risk of distant metastasis. Prospective evaluation of Ki-67 should be carried out in patients with soft tissue sarcomas for planning adjuvant treatment modalities

show abstract

Clinicopathological study of benign soft tissue neoplasms: Experience at rural based tertiary teaching hospital

Cited by 3 publications

References 5 publications

A Retrospective Study of Soft Tissue Tumors - Role of Histomorphology in Diagnosis

A Retrospective Study of Soft Tissue Tumors - Role of Histomorphology in Diagnosis

Clinico-pathological study of soft tissue tumors

Histopathological Study of Soft Tissue Tumours and Correlation of Histologic Grade of Sarcomas With Proliferative Marker Ki-67

Contact Info

Product

Resources

About