Clinicopathological profile and course of malignant pleural effusion in a tertiary care teaching hospital in western Uttar Pradesh with special reference to lung cancer

Agrawal, Anurag; Tandon, R. N.; Singh, Lalit; Chawla, Aakanksha

doi:10.4103/0970-2113.168122

Cited by 7 publications

(3 citation statements)

References 4 publications

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“…Metastatic pleural neoplasms are more common compared with the primary pleural neoplasms (1,2). The same was observed in the current study with 42.9% of primary neoplasms compared with 57.1% of secondary pleural tumors.…”

Section: Discussionmentioning

confidence: 99%

“…Metastatic pleural tumors are more common malignant neoplasms of pleura, lungs, breast, and hematologic malignancy (lymphoma) are the common primary metastasizing neoplasms (1). In the current study, pulmonary adenocarcinoma was the most common followed by breast.…”

Section: Discussionmentioning

confidence: 99%

“…Metastatic carcinomas greatly outnumber primary neoplasms of the pleura including the diffuse malignant mesothelioma (MM). Metastatic involvement of the pleura is observed in lung cancer, lymphoma, breast and carcinomas of the female genital tract, and gastrointestinal tract in the descending order of frequency (1). A wide spectrum of lesions categorized as benign, low malignant potential, and malignant involved pleura.…”

Section: Introductionmentioning

confidence: 99%

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Histomorphological and Immunohistochemical Analysis of Pleural Neoplasms

et al. 2018

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Lung neoplasms; Mesothelioma;Pleura; Sarcoma; Carcinoid Background & objective: Primary pleural neoplasms are rare entities compared with the pleural involvement by metastatic carcinoma.The current study aimed at investigating the complete spectrum of pleural neoplasms and differentiating between them with the aid of immunohistochemistry (IHC).Methods: Consecutive pleural biopsy specimens positive for a neoplasm, both primary and metastatic, were included in the study. Diagnosis or a differential diagnosis was suggested on histopathology confirmed by a panel of IHC markers such ascytokeratin(AE1/AE3), epithelial membrane antigen (EMA),vimentin, calretinin, CD34, CD99, SMA,bcl2, S100, CK7,CK20,TTF1,GCDFP, HMB45, LCA, synaptophysin, chromogranin, and naspsin.Results: A total of 35 cases of pleural neoplasms included 15 (42.9%) primary pleural neoplasms and 20 (57.1%) metastatic carcinoma. Synovial sarcoma, malignant mesothelioma (MM), and solitary fibrous tumor (SFT) accounted for 14.2%,11.4%, and 8.5% of metastatic cases, respectively. Epithelioid sarcoma(ES), neuroendocrine carcinoma, and inflammatory myofibroblastic tumor were less common, each contributing to 2.9% of pleural neoplasms. Among the 20 cases of metastatic carcinoma, 13 were from the lung and 7 from the breast. Lung neoplasms metastasizing to the pleura were adenocarcinoma (n=12) and atypical carcinoid (n=1).Conclusion: Analysis of histopathological pattern along with a panel of appropriate IHC markers distinguished the rare entities of pleural neoplasms essential to determine the prognosis and treatment modality.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Histomorphological and Immunohistochemical Analysis of Pleural Neoplasms

et al. 2018

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Survie des pleurésies malignes et paramalignes à Ouagadougou

Bambara

Ouédraogo

Maïga

et al. 2016

Revue de Pneumologie Clinique

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Clinico-pathological profile of lung cancer in North Indian population

Bhaskar

Singh

et al. 2018

IJRDPL

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Lung cancer is the most common cancer representing approximately 12% of all new cancers. It is also the most frequent type of cancer in males and remains the most a common cause of cancer-related mortality in both sexes. An increasing incidence of lung cancer has been observed in India. We studied the clinical and pathological profile of patients with lung cancer in a tertiary care center. We performed a retrospective analysis of histopathologically proven cases of bronchogenic carcinoma admitted in our hospital. In our study we included 203 patients with confirmed cases of lung cancer. Male to female ratio was 8.2:1. The common age group being 40-60 years, 9.86% of the patients were less than 40 years old age. Smoking was found to be the main risk factor for 81.77% patients. The most frequent symptom was a cough (72.90%) followed by fever (58.12%). The most common radiological presentation was mess lesion (46.31%). The most common histopathological type was squamous cell carcinoma (SCC) (44.83%) followed by adenocarcinoma (19.78%) and small cell lung carcinoma (SCLC) (16.75%). The majority patients (73.29%) were diagnosed in the later stages of the disease (3b and 4). Squamous cell carcinoma was the most frequent histopathological form. Smoking remains the major risk factor for lung cancer.

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Clinicopathological profile and course of malignant pleural effusion in a tertiary care teaching hospital in western Uttar Pradesh with special reference to lung cancer

Cited by 7 publications

References 4 publications

Histomorphological and Immunohistochemical Analysis of Pleural Neoplasms

Histomorphological and Immunohistochemical Analysis of Pleural Neoplasms

Survie des pleurésies malignes et paramalignes à Ouagadougou

Clinico-pathological profile of lung cancer in North Indian population

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