“…NK cell lymphocytosis of uncertain clinical significance has also been described, and may have restricted expression of KIR antigens, CD158a, CD158b, CD158e, and CD94/NKG2A, suggesting clonality. 6,17 Of interest, increased NK cells, cytotoxic T-cells and gammadelta T-cells have been described at diagnosis in chronic myeloid leukemia (CML) and multiple myeloma, and are often monoclonal or oligoclonal. In addition, lymphocytosis has been described in patients with CML receiving treatment with the second generation tyrosine kinase inhibitor Dasatinib.…”