Clinicopathologic review of eruptive pseudoangiomatosis in Korean adults: report of 32 cases

Abstract

Any clear relationship between EP and exposure to allergens or insect bites has yet to be elucidated. In patients in whom EP occurs on non-exposed sites, drugs and food should be considered as possible causative agents. Intravascular neutrophil infiltration on histology can be helpful in diagnosing EP.

Eruptive pseudoangiomatosis in two children with acute lymphoblastic leukemia

“…Eruptive pseudoangiomatosis is characterized by the sudden appearance of a few to numerous, 2–5 mm in size, bright red hemangioma‐like papules, surrounded by a white halo, that disappear after pressure and refill on release . They affect exposed sites, although they can occur on the whole body . EPA is asymptomatic and resolves spontaneously within 1–2 weeks …”

Pityriasis rosea, Gianotti-Crosti syndrome, asymmetric periflexural exanthem, papular-purpuric gloves and socks syndrome, eruptive pseudoangiomatosis, and eruptive hypomelanosis: do their epidemiological data substantiate infectious etiologies?

“…EP has been reported for all ages, from neonates, 203 infants, 203 children, 197-199 , 206 , 208 , 216 adults, 199-202 , 204 , 209-214 to the elderlies. 211 , 213 , 214 This wide range of age argues against a single virological cause. Sexual preponderance has not be reported for EP.…”

“…EP was reported to be associated with insect bites 210 , 211 , 213 and with immunocompromising states, such as post-renal transplant on immunosuppressive agents, 201 pemphigus vulgaris on systemic corticosteroids, 205 and chemotherapy for Hodgkin lymphoma. 215 These reports suggest that EP might be the final common pathway by multiple factors which are remotely related to each other otherwise.…”

Multiple angioma‐like papules with a perilesional halo in a dark skin adult

“…1 Its aetiology is unknown, but it has been considered a dermal hypersensitivity reaction associated with viral infections (Echovirus, Coxsackie B, Epstein-Barr, Cytomegalovirus), drugs (including chemotherapy), foods, herbal medicine (deer horn, gingko nut, Kalopanax pictus), allergens and malignancies (acute lymphoblastic leukaemia). [2][3][4] Eruptive pseudoangiomatosis manifests as lesions consisting of small erythematous angioma-like papules with a perilesional pale halo, most commonly found in the extremities. 3 A prodrome of fever, sore throat or gastrointestinal symptoms is usually present.…”

“…[2][3][4] Eruptive pseudoangiomatosis manifests as lesions consisting of small erythematous angioma-like papules with a perilesional pale halo, most commonly found in the extremities. 3 A prodrome of fever, sore throat or gastrointestinal symptoms is usually present. 1,3 It tends to resolve spontaneously in 1-2 weeks in children and 1-3 months in adults without sequelae; nevertheless, recurrences have been reported.…”