Clinico-pathological profile of head and neck malignancies at University College Hospital, Ibadan, Nigeria

Adisa, Akinyele Olumuyiwa; Adeyemi, B F; Oluwasola, A O; Kolude, Bamidele; Akang, E. E. U.; Lawoyin, J O

doi:10.1186/1746-160x-7-9

Cited by 24 publications

(59 citation statements)

References 29 publications

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“…This is relatively low compared to studies conducted in other regions of the country. 14,16,[20][21][22][23] The male to female ratio in this study 1.2: 1. This falls within the range of 1.1 to 2.3:1 found in most studies around the country.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of head and neck tumours in Calabar, South Eastern Nigeria

2016

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Head and neck tumours constitute a wide spectrum of heterogeneous tumours affecting different anatomical sites in the head and neck region, with varying histology and biological behaviors.The different sites include sinonasal, nasopharyngeal, parapharyngeal, oral and oropharyngeal, hypopharyngeal, laryngeal, otologic, orbital, thyroid and parathyroid, and salivary gland tumours. The different subtypes include squamous cell carcinomas, paranasal sinus and nasopharyngeal carcinomas, salivary gland cancers, melanomas, sarcomas, lymphomas and lymphatic tumours, orbital tumours, thyroid and parathyroid gland tumours and other neuroendocrine tumours. [1][2][3] Malignancies in the head and neck region though relatively rare, compared to other regions of the body, they contribute significantly to morbidity and mortality in affected patients. Background: Malignancies in the head and neck region though relatively rare, compared to other regions of the body, they contribute significantly to morbidity and mortality in affected patients. In Nigeria, the burden of managing head and Neck malignancies is enormous and there is yet to be a unified record of nation-wide incidence of malignancies involving the head and neck region despite the fact the head and neck malignancies have been diagnosed and documented since the 1960's. The histological pattern and frequency however seems to have some slight variation depending on the region and the identified aetiological risk factors. Aims and Objectives:The aim of this study was to determine the pattern of head and neck tumours seen in the region and the commonest malignancies in the cohort. By comparing the relative prevalence of the lesions with other centers in the country and international published literature we hope to make a case for proper tumour registry and move for nation-wide studies. Materials and Methods:The authors reviewed the histopathological data of the tumor registry at the University of Calabar Teaching Hospital, a major referral Center in South-Eastern Nigeria between 2005 and 2012. All cases of head and Neck tumours with histological diagnosis were included for analysis, their demographic data were obtained and analyzed using SPSSv16. Results: Two hundred and twenty-five specimens from the head and neck region were analyzed during this 6 year period giving an average of 34 cases per year. The Male:Female ratio was 1.2:1. The age range was from 2 years to 76 years with overall mean of 32.7 years. One hundred and forty-five cases (63.3%) were benign while 84 malignant cases (36.7%) were recorded for the study period. The average number of new malignant cases seen was 14 per year. Malignancies were commoner in those less than 50 years of age and were mostly those of epithelial origin. Conclusion: Variations in the regional demographics of head and neck tumors in the country could be accounted for by the differences in data collection methods and certain aetiological factors that may be unique to those regions. A proper tumor registry in each region, harmonized with ...

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Section: Discussionmentioning

confidence: 99%

Prevalence of head and neck tumours in Calabar, South Eastern Nigeria

2016

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“…5,6 Malignancies in head and neck region are the tenth most common cancers in the world and are an important cause of morbidity and mortality in affected patients. 3,7 Malignant lesions can present as primary as well as secondaries from other organs.…”

Section: Introductionmentioning

confidence: 99%

Histopathological patterns of head and neck lesions - a two year retrospective hospital based study

Sharma¹,

Sharma²,

Gandhi³

et al. 2017

Int J Res Med Sci

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Background: Head and neck lesions include a spectrum of pathological lesions ranging from simple benign to highly malignant entities. These lesions contribute significantly to morbidity and mortality of patients. The aim of this study was to determine the histological patterns of head and neck lesions, both non- neoplastic and neoplastic and to analyse the data in relation to age, gender, topography.Methods: A two year retrospective study was conducted in the Post Graduate Department of Pathology, ASCOMS and Hospital and histopathological data pertaining to all head and neck lesions was reviewed. Each case was analysed with respect to age, gender, site and histological type.Results: One hundred and forty-five cases from the head and neck region were analysed during this two-year period. Age range was from 3 months to 85 years with maximum cases in the age group of 21-50 years (51.03%). The Male: Female ratio was 1.37:1. In our study, 53.79% benign, 24.13% inflammatory and 22.06% malignant cases were recorded. Maximum number of benign lesions was in the age group of 21-50 years. Malignancies were noted to be higher in ages 51 years and above. Squamous cell carcinoma was the most common malignancy observed.Conclusions: We conclude that site specific data like this is helpful in evaluating patterns of head and neck lesions and augment the base line data of institute and the region.

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“…The two most common head and neck cancers in their series were SCC, which accounted for 47.8% of cases, followed by lymphomas which accounted for 19.3% [53]. Adisa et al [27] reported that the epithelial malignancies (carcinomas) constitute 73.4% of all the cases while Lymphomas and sarcomas were 17.5% and 8.9% of cases respectively.…”

Section: Histopathological Types Of the Oral Cancersmentioning

confidence: 99%

“…In our environment, oral cancer is one of the most common lethal diseases that will be encountered in dental practice [13,20,27]. It is frequently diagnosed in late stages because most patients present to the hospital late into the course of the disease for treatment hence a poor prognosis.…”

Section: Awareness Of Oral Cancermentioning

confidence: 99%

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Oral Cancer- The Nigerian Perspective

Okoh¹,

Okoh²

2017

J Mol Biomark Diagn

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Study background: In our environment, oral cancer is one of the most common lethal diseases encountered in dental practice. It is frequently diagnosed in the late stages because most patients present late in the course of the disease. This may be attributed to their low socioeconomic status, illiteracy, and some traditional beliefs in alternative native therapies. Some authors have reported on oral cancers specifically in their individual geographic settings; however, there is a paucity of reviews on Oral cancers generally in our environment. This study aims to review the prevalence, awareness and clinicopathologic patterns of oral cancers across the different geographic zones in Nigeria.Methods: Information was sourced from journals, electronic data base such as Medline, Pubmed, Elsevier ScienceDirect and personal research work.Result: Several prevalence rates have been reported in different geopolitical locations in our environment. Orofacial carcinomas were reported mostly in the older age groups while the Orofacial sarcomas were found in the slightly younger age groups. Squamous cell carcinoma was the predominant histopathological type. There is a low level of awareness of these lesions among the low socio-economic groups which makes them present late in our health care facilities hence a poor prognosis. Conclusion:There is a need for increased awareness, advocacy and preventive care and early detection.

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Clinico-pathological profile of head and neck malignancies at University College Hospital, Ibadan, Nigeria

Cited by 24 publications

References 29 publications

Prevalence of head and neck tumours in Calabar, South Eastern Nigeria

Prevalence of head and neck tumours in Calabar, South Eastern Nigeria

Histopathological patterns of head and neck lesions - a two year retrospective hospital based study

Oral Cancer- The Nigerian Perspective

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