“…Li Fanbing [36] For the treatment of KOA, the principle of deficiency replenishment is implemented, based on liver and kidney deficiency, it is divided into three types: qi and blood deficiency, cold and wet obstruction, and humid heat flow injection. Zhu Yuelan [37] added or subtracted drugs for the treatment of OA from four aspects: (1) nourishing the liver and kidneys, activating blood circulation and removing stasis: Fang Zhong often added Chinese medicines that replenish kidney and blood, such as bone crushing, continuity, chicken blood vine, etc. ; (2) Dispel wind and cold, dehumidify and circulate: often add weed, sea tung bark, Qin Jiao; (3) Relieve liver depression, clear the mind and calm the mind: Fang Zhong often adds calamus, tulip, etc.…”