Clinical variants of lichen planus

Abstract

SummaryLichen planus is characterized by lichenoid, polygonal papules with fine white lines, called Wickham striae. Lesions most commonly occur on the limbs and on the dorsal aspect of the trunk. At the same time often leukoplakia of mucous membranes as well as nail disorders are seen.There are numerous variants of lichen planus which can be distinguished from the classical form on the basis of morphology and distribution of the lesions. The typical primary lesion of lichen planus may be replaced by other forms, such as patches, hyperkeratoses, ulcerations, or bullous lesions. Moreover, distribution patterns of these lesions may vary and include erythrodermic, inverse or linear arrangements. In contrast to these numerous clinical features, histologic findings remain characteristic in the variants, so that the diagnosis can be made securely. Differential diagnoses of lichen planus include diverse dermatoses such as bullous pemphigoid or paronychia.

Cutaneous Manifestations of Diabetes Mellitus

“…ceous, flat-topped, polygonal papules distributed mainly in flexural aspects of arms and legs and rarely can appear on the trunk ("Blaschkoid" or "zosteriform") and inverse ("intertriginous") (48). Variants may include ulcerative and perforating types.…”

“…It is classically described as the "four Ps": pruritic, purple (violaceous), polygonal, and papules or plaques. Papules may be isolated and a few millimeters in diameter or may coalesce to form larger plaques (48). Fine white lines may be visible on the surface of papules or plaques and are known as "Wickham's striae."…”

A Case of Lichen Planus with Palmoplantar Involvement

“…Klasik liken planusun karakteristik lezyonu birkaç milimetre boyutlarında mor renkli, düz yüzeyli, poligonal papüllerdir ve predileksiyon bölgeleri; el bileği, ayak bileği, lomber bölge ile oral ve genital mukozalardır (1). Klasik formu dışında anüler, atrofik, büllöz, hipertrofik, foliküler, lineer, mukozal, tırnak liken planusu gibi farklı klinik görünümlerde liken planus varyantları da vardır.…”

Lichen ruber planus: etiology, pathogenesis, clinical entities, histological pattern and the main treatment principles

“…Количе-ство высыпаний различно: от единичных (в полости рта, на половых органах) до множественных, по-крывающих значительные участки тела так, что мо-жет создаваться впечатление сплошного поражения кожи, иногда по типу эритродермии. Субъективно больных беспокоит зуд [5].На поверхности сформировавшихся относи-тельно крупных (0,5 мм в диаметре) узелков можно обнаружить патогномоничную для заболевания сет-ку Уикхема, характеризующуюся опаловидными бе-лыми или сероватыми точками и полосками. Ее формирование объясняют неравномерным грануле-зом.…”

“…Количе-ство высыпаний различно: от единичных (в полости рта, на половых органах) до множественных, по-крывающих значительные участки тела так, что мо-жет создаваться впечатление сплошного поражения кожи, иногда по типу эритродермии. Субъективно больных беспокоит зуд [5].…”