Clinical Validity of Cerebral Oxygen Saturation Measured by Time-resolved Spectroscopy During Carotid Endarterectomy

Yoshitani, Kenji; Kuwajima, Ken; Irie, Tomoya; Inatomi, Yuzuru; Miyazaki, Atushi; Iihara, Koji; Ohnishi, Yoshihiko

doi:10.1097/ana.0b013e31827ee0cf

Cited by 20 publications

(4 citation statements)

References 20 publications

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“…The six-wavelength TD-DOS system (TRS-21-6W) was constructed based on a threewavelength system we had previously developed (TRS-20, Hamamatsu Photonics K.K.) to measure hemoglobin concentrations in human muscle, brain, and breast tissue [21][22][23][24][25]. That system, the TRS-20, is a dual-channel TD-DOS system that uses three wavelengths in the 750 nm to 850 nm range.…”

Section: Instrumentationmentioning

confidence: 99%

Stable tissue-simulating phantoms with various water and lipid contents for diffuse optical spectroscopy

Ohmae

Yoshizawa

Yoshimoto

et al. 2018

Biomed. Opt. Express

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We introduced a method for producing solid phantoms with various water-to-lipid ratios that can simulate the absorption, and to some extent the scattering characteristics of human breast tissue. We also achieved phantom stability for a minimum of one month by solidifying the emulsion phantoms. The characteristics of the phantoms were evaluated using the six-wavelength time-domain diffuse optical spectroscopy (TD-DOS) system we developed to measure water and lipid contents and hemoglobin concentration. The TD-DOS measurements were validated with a magnetic resonance imaging system.

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Section: Instrumentationmentioning

confidence: 99%

Stable tissue-simulating phantoms with various water and lipid contents for diffuse optical spectroscopy

Ohmae

Yoshizawa

Yoshimoto

et al. 2018

Biomed. Opt. Express

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“…Cerebral oxygen saturation (ScO 2 ) represents mixed oxygen saturation of cerebral arterial and venous (25 and 75 %) [ 1 ], and provides the status of cerebral hemodynamics in multiple pathological processes [ 2 , 3 ]. The level of ScO 2 depends on the balance of cerebral oxygen supply and demand.…”

Section: Introductionmentioning

confidence: 99%

Cerebral oxygen saturation after multiple perioperative influential factors predicts the occurrence of postoperative cognitive dysfunction

et al. 2015

BMC Anesthesiol

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BackgroundPostoperative cognitive dysfunction (POCD) is a frequent complication in elderly patients undergoing major non-cardiac surgery, but its etiology is still unclear. Cerebral oxygen saturation (ScO2) represents the balance of cerebral oxygen supply and demand. The aim of present study was to evaluate the relationship between perioperative ScO2 and POCD, and to verify the hypothesis that the value of ScO2 after multiple perioperative influential factors could predict POCD in elderly patients undergoing total knee arthroplasty (TKA).MethodsSeventy eight Patients aged more than 65 years undergoing elective TKA with intrathecal anesthesia were enrolled. Cognitive functions were assessed one day before and 6 days after surgery, and POCD were defined according to ISPOCD. Demographics were recorded. Perioperative ScO2, blood pressure (BP), blood gas analysis and other clinical data were monitored and recorded, then the decrease of ScO2, BP and PaO2 after influential factors were calculated.ResultsPOCD occurred in 15 patients (19.2 %). BP decreased after anesthesia induction and tourniquet deflation, and PaO2 decreased after cement implantation, then percentage decrease of BP was higher in POCD group. ScO2 of POCD group is significantly lower than non-POCD group (P < 0.05), and the absolute value and percentage decrease of ScO2 became significant between two groups after multiple influential factors. ScO2 after all influential factors (anesthesia induction, cement implantation and tourniquet deflation) had the best predictive performance for POCD (AUC = 0.742), and the optimal threshold was 66.5 %.ConclusionsPerioperative ScO2 of patients with POCD is lower than patients without POCD. ScO2 after multiple perioperative influential factors could be an effective predictor for POCD, which reveal an important role of ScO2 decrease in the development of POCD and provide possible treatment target.

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“…[ 10 ] It also provides the status of cerebral hemodynamics in multiple pathological processes. [ 11 , 12 ] The level of rSO 2 depends on the balance between cerebral oxygen supply [ 13 ] and demand. [ 14 ] Several factors that influence cerebral oxygen saturation have been described.…”

Section: Discussionmentioning

confidence: 99%

Improvement in cerebral oxygen saturation with sinus conversion during off pump coronary artery bypass graft: A case report

2023

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Rationale: Near-infrared spectroscopy (NIRS) is a noninvasive bedside tool for monitoring regional cerebral oxygen saturation (rSO 2 ). The sinus conversion of atrial fibrillation (AF) was shown to be responsible for increasing rSO 2 . However, the reason for this improvement has not yet been clearly explained.Patient concerns: We report the case of a 73-year-old woman who underwent cardioversion during an off-pump coronary artery bypass under NIRS and live hemodynamic monitoring.Interventions: Unlike previous studies that failed to control and compare all conditions during procedures, this case showed real-time fluctuating hemodynamic and hematological values, such as hemoglobin (Hgb), central venous pressure (CVP), mean arterial pressure (MAP), cardiac index (CI), left ventricular end-diastolic pressure (LVEDP), and SVO 2 .Outcomes: The rSO 2 increased immediately after cardioversion and decreased during the obtuse marginal (OM) graft and after AF was obtained. However, no other hemodynamic data showed the same or opposite directional changes in the rSO 2 .Lessons: Significant instantaneous changes were observed in rSO 2 using NIRS after sinus conversion, without obvious hemodynamic alterations in the systemic circulation or other monitoring values.

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Clinical Validity of Cerebral Oxygen Saturation Measured by Time-resolved Spectroscopy During Carotid Endarterectomy

Abstract: ScO2 measured by TRS and SjO2 showed narrow limits of agreement. Reduced ScO2 was significantly associated with impaired cerebral hemodynamics.

Cited by 20 publications

References 20 publications

Stable tissue-simulating phantoms with various water and lipid contents for diffuse optical spectroscopy

Stable tissue-simulating phantoms with various water and lipid contents for diffuse optical spectroscopy

Cerebral oxygen saturation after multiple perioperative influential factors predicts the occurrence of postoperative cognitive dysfunction

Improvement in cerebral oxygen saturation with sinus conversion during off pump coronary artery bypass graft: A case report

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