Clinical utility of ozone therapy in dental and oral medicine

Suh, Yiji; Patel, Shrey; Re, Kaitlyn; Gandhi, Jason; Joshi, Gunjan; Smith, Noelle B.; Khan, Sardar

doi:10.4103/2045-9912.266997

Cited by 88 publications

(83 citation statements)

References 23 publications

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“…We identified 26 citations of which 10 systematic reviews (Albedah et al, 2013;Azarpazhooh & Limeback, 2008;Brazzelli et al, 2006;Deepthi & Bilichodmath, 2020;German et al, 2013;Moraschini et al, 2020;Santos et al, 2020;Sharda et al, 2021;Silva et al, 2020;Sridharan & Sivaramakrishnan, 2021) and 16 narrative reviews (Almaz & Sönmez, 2015;Chirumbolo et al, 2021;Domb, 2019;Gupta & Mansi, 2012;Haghighat & Oshaghi, 2020;Lacerda et al, 2021;Lio et al, 2020;Mohammadi et al, 2013;Nogales et al, 2008;Re et al, 2020;Seidler et al, 2008;Suh et al, 2019;Swanson et al, 2021;Tiwari et al, 2017;Trevor Burke, 2012;Tricarico et al, 2020); met the criteria for inclusion in the Map. Most of the reviews were published in the 2008, 2012 and 2014.…”

Section: Resultsmentioning

confidence: 99%

Experience with the evidence map in oral ozone therapy - importance for integrative and complementary health practices

Cordon

Laganá

Traina

et al. 2021

RSD

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medical and dental treatment in the form of ozonized water and oxygen / ozone gas mixture and associated with photobiomodulation therapy. The evidence map was based on the 3iE evidence searched in the databases: LILACS, PubMed, EMBASE and Cochrane Library, seeking systematic and narrative reviews, analyzed in an excel characterization spreadsheet. Three independent literature reviewers screened the systematic review search output blinded at the software Rayyan. The full-text publications were screened against the specified inclusion criteria by thre independent reviewers; disagreements were resolved through discussion. Forty-two studies were found, 16 of which were systematic reviews and 26 narrative reviews, published between 2006 and 2021, with different levels of confidence. The intervention that most appeared in the literature was oral ozone therapy as a bacterial colony reduction and decontamination agent, with emphasis on topical oxygen-ozone gas mixtures, topical ozonized water. Oral ozone therapy can bring benefits to clinical practice and patients. The evidence map provides an easy visualization of valuable information for patients, health practitioners and managers, in order to promote evidence-based complementary therapies.

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Section: Resultsmentioning

confidence: 99%

Experience with the evidence map in oral ozone therapy - importance for integrative and complementary health practices

Cordon

Laganá

Traina

et al. 2021

RSD

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“…More clinical studies with standardized trials are necessary to ensure greater knowledge about the use of ozonated water in oral surgical procedures. [ 28 29 ]…”

Section: Discussionmentioning

confidence: 99%

Comparison of efficacy of ozonated water, normal saline, and povidone-iodine after surgical removal of impacted mandibular third molars: A cross-sectional study

Ghosh¹,

Bhardwaj

Koyalada³

et al. 2020

J Family Med Prim Care

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Background: Surgical extraction of mandibular third molars is an important and one of the most frequently performed operative procedures in dentistry. There are a variety of postoperative complications that may follow this procedure. These include pain, trismus, infection, dry socket, or alveolar osteitis. Numerous techniques have been used for reducing these morbid conditions. These range from flap designs, suture placement, use of various irrigating solutions, etc., Aim: The present study aimed to compare the effectiveness of three irrigating solutions: Ozonated water, normal saline, and povidone-iodine in reducing postoperative complications following surgical removal of impacted mandibular third molars. Materials and Methods: A total of 100 study participants formed the sample size of this study. Study subjects were categorized into three groups: Group I (third molar surgeries using ozonated water), Group II (third molar surgeries with normal saline irrigation), and Group III (third molar surgeries using povidone-iodine irrigation). Parameters studied postoperatively were alveolar osteitis (dry socket), pain, trismus, and infection after a week interval. All data obtained were entered in Microsoft Excel 2007 worksheets and Analysis of Variance (ANOVA) as a statistical tool was employed. A P value of < 0.01 was considered statistically significant. Results: It was found that ozonated water provided the best statistically proven results with comparison to normal saline and povidone-iodine in reducing the incidence of alveolar osteitis or dry socket and pain. No statistically significant difference was observed in the incidence of trismus and infection rate among three studied groups. Conclusion: Ozonated water is the best irrigating solution when compared to normal saline and povidone-iodine in terms of reduction in pain and dry socket after a 1-week duration.

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“…Ozone therapy has proven successful in dentistry with managing wound healing in the oral cavity, oral lichen planus, gingivitis and periodontitis, halitosis, osteonecrosis of the jaw, post-surgical pain, dental caries, plaque and biofilms, root canals, dentin hypersensitivity, temporomandibular joint disorders and teeth whitening. Even though ozone has been used for disinfection of operating rooms since 1856 [44], today it is not the first-choice method.…”

Section: Ozone Generatorsmentioning

confidence: 99%

Air disinfection procedures in the dental office during the COVID-19 pandemic

Tysiąc-Miśta¹,

Dubiel²,

Brzoza³

et al. 2020

Med Pr

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The outbreak of coronavirus disease 2019 (COVID-19) generated a huge pressure on health care systems worldwide and exposed their lack of preparation for a major health crisis. In the times of a respiratory disease pandemic, members of the dental profession, due to having a direct contact with the patients' oral cavity, body fluids and airborne pathogens, are exposed to a great occupational hazard of becoming infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The authors carried out a systematic literature search using the main online databases

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Clinical utility of ozone therapy in dental and oral medicine

Cited by 88 publications

References 23 publications

Experience with the evidence map in oral ozone therapy - importance for integrative and complementary health practices

Experience with the evidence map in oral ozone therapy - importance for integrative and complementary health practices

Comparison of efficacy of ozonated water, normal saline, and povidone-iodine after surgical removal of impacted mandibular third molars: A cross-sectional study

Air disinfection procedures in the dental office during the COVID-19 pandemic

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