Clinical Uses of Seromucoid Estimation

Abstract

Preliminary studies have been made on the subcellular components of the livers of animals given radioactive glucosamine. Microsomes, lysosomes and mitochrondia are strongly labelled.Preliminary studies have been made of the degradation rate of serum protein labelled with C-14-g1ucosamine in rats bearing the Walker 256 tumor. A faster degradation rate of total serum protein labelled by these means was present in the tumour-bearing animals. A faster rate was

Serum α-1-acid glycoprotein as an index of dissemination in breast cancer

“…Therefore, in combination with direct investigations of sites of metastases, many systemic changes secondary to dissemination may prove very useful to the clinician. One such investigation is the estimation of serum glycoproteins (such as orosomucoid), which are elevated in many disease states (Winzler and Smith, 1948;Keyser, 1954;Shetlar, 1961;Easton et al, 1962;Keyser, 1964;Bacchus et al, 1967). Patients with malignant diseases are amongst those with elevated serum orosomucoid levels.…”