Clinical Use of a Pronuclear Stage Score Following Intracytoplasmic Sperm Injection (ICSI) Compared with Chromosomal Status

Rocha, C.C.; Iaconelli, Assumpto; Rossi-Ferragut, Lia Mara; Vieira, Marcelo; Farah, L; Borges, Edson

doi:10.1016/s0015-0282(00)01228-0

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“…Spermatozoa retrieved from men with severe male factor may show some abnormalities in terms of MTOC or centrioles, on the basis of the fact that zygote was an abnormal morphology (32,33), rarely progress well, and rarely form blastocysts (9). Despite this, in our previous work (34,35) we compared PN morphology, transfer day morphology, and PGD results for chromosomes X, Y, 13, 18, and 21. Our results have showed that preembryos with close or aligned PN exhibit higher percentage of normal PGD results for the analyzed chromosomes (56%) compared to preembryos with unequal or separated PN (45.5%).…”

Section: Discussionmentioning

confidence: 99%