2003
DOI: 10.1023/a:1021286119979
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Abstract: PN classification associated with transfer day morphology is valuable additional noninvasive criterion for elective embryo transfer, mainly in the cases with severe male factor.

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Cited by 16 publications
(3 citation statements)
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“…This hypothesis is further substantiated by the present observation that GH administration in this group of patients did not only improve the morphological quality of the oocytes obtained, but it also increased the total number of fertilized oocytes (zygotes), that of normal zygotes and that of high-quality embryos, as judged by their morphological appearance. Among these characteristics, that of the zygote quality seems to be of particular importance, since it was previously shown that zygote pronuclear morphology is related not only with IVF clinical outcomes ( 25 28 ) and the rate of embryo development to the blastocyst stage ( 27 ), but also with the normal ploidy of the resulting blastocysts ( 29 31 ). When used in combination with further evaluation of embryo morphology during subsequent stages of preimplantation development, the prognostic value of zygote morphology, as to the probability of establishing a normal pregnancy, was further enhanced ( 32 , 33 ).…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…This hypothesis is further substantiated by the present observation that GH administration in this group of patients did not only improve the morphological quality of the oocytes obtained, but it also increased the total number of fertilized oocytes (zygotes), that of normal zygotes and that of high-quality embryos, as judged by their morphological appearance. Among these characteristics, that of the zygote quality seems to be of particular importance, since it was previously shown that zygote pronuclear morphology is related not only with IVF clinical outcomes ( 25 28 ) and the rate of embryo development to the blastocyst stage ( 27 ), but also with the normal ploidy of the resulting blastocysts ( 29 31 ). When used in combination with further evaluation of embryo morphology during subsequent stages of preimplantation development, the prognostic value of zygote morphology, as to the probability of establishing a normal pregnancy, was further enhanced ( 32 , 33 ).…”
Section: Discussionmentioning
confidence: 99%
“…Oocytes were attributed one of the four cumulative scores, from A (the best one) to D (the worst one), taking into account the oocyte shape, cytoplasmic granularity, the presence of intracytoplasmic vacuoles, the form of the zona pellucida and the perivitelline space, and the size and morphology of the first polar body ( 37 ). Zygotes and cleaving embryos ( Figure 1 ) were scored as described previously ( 25 28 , 32 ). Briefly, cleaving embryos were scored according to the number of cells, the shape and regularity of the cells, and the volume occupied by anucleate fragments ( Figure 1 ).…”
Section: Methodsmentioning
confidence: 99%
“…Among the treatment modalities offered to infertile couples, those utilizing assisted reproductive technologies (ART) are associated with the highest success rates [2]. ART procedures involve retrieval of oocyte(s) from a woman's ovaries, their fertilization in vitro in a laboratory, and the return of the resulting embryo to the woman's body or donation to another woman [3]. More than 99% of all ART procedures involves the transfer of the resulting embryos into the woman's uterus through cervix [2], and are termed in vitro fertilization-embryo transfer (IVF-ET).…”
Section: Infertility and Assisted Reproductive Technologies (Art)mentioning
confidence: 99%