“…Sulfonamides of low solubility, when given in large doses or to dehydrated or acidotic patients, will readily obstruct the urinary tract, thereby injuring the kidney (167). Tubular necrosis with hematuria and acute renal failure also may occur without demonstrable sulfonamide Crystallization .…”
“…Sulfonamides of low solubility, when given in large doses or to dehydrated or acidotic patients, will readily obstruct the urinary tract, thereby injuring the kidney (167). Tubular necrosis with hematuria and acute renal failure also may occur without demonstrable sulfonamide Crystallization .…”
“…This seems unlikely because sulphonamide could hardly cause damage to the nervous system [Langscope. 1943;Lehr, 1957], There is only one report of serious effect of sulphonamide [Poliak and Ziskind. 1953], but this patient also had SLE while on the drug.…”
Myelopathy is a rare complication of systemic lupus erythematosus (SLE). Only 34 cases have been fully described in the literature. 5 other cases have been listed among large surveys of SLE patients. It is particularly unusual to find evidence of spinal cord involvement as the presenting feature of the disease. 2 cases are described in which SLE presented as a myelopathy and both made a satisfactory recovery with steroid treatment. The literature concerning SLE-myelopathy is reviewed.
“…Zur Gewähr leistung konstanter Blut-und Gewebsspiegel mussten diese Mengen teilweise in vierstündlichem Abstand verabfolgt werden. Neben häufigen Unverträglichkeitserscheinungen von seiten des MagenDarm-Traktes kann es durch die hohen Urinkonzentrationen der meist relativ schwer löslichen Sulfonamide (besonders ihrer Acetylderivate) zur Auskristallisation in den Nierenkanälchen kommen (23,24). Eine weitere Gefahr, die vornehmlich den Pädiater interessiert, besteht in der vor allem beim jungen Säugling vorkommenden Bildung von Hämiglobin und von HEiNZSchen Innenkörpern mit den Folgen der Innenkörperanämie (4,8,14,15,18 …”
Section: H S C H ö N F E L D U N D S Se I D Lunclassified
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