Clinical Survey of Pseudoexfoliation Syndrome

Abstract

OBJECTIVE: Assess the prevalence ‎of PEX and identify the associated glaucoma and ‎cataract.‎
 
 STUDY DESIGN & METHODOLOGY: A sample of 6,650 patients (age ≥40 years) that attended the single ‎ophthalmic private clinic for ‎different complaints, for five years (January 2013 until January 2018), those diagnosed with ‎PEX ‏enrolled in this study, with a total number of 296 ‎patients.‎
 
 RESULTS: ‎14 (4.7%) patients with age from 40-49 years, 54(18.2%) from 50-‎‎59 years, 102 (34.5%) from ‎‎60-69 years, and 126(42.6%) equal or older ‎than 70 years. Close sex frequencies were observed, ‎with 153(51.7%) ‎males, and 143(48.3%) females. In the current study, the prevalence of ‎PEX ‎was 4.45% (95% confidence interval (CI), ‎‎3.98-4.97). There was a statistically insignificant ‎relationship between PEG ‎or advanced glaucoma with age or sex, but cataract was ‎significantly ‎associated with older age and male sex.‎
 
 CONCLUSION: The prevalence of Pseudoexfoliation syndrome was 4.45%, with a sharp increase after the ‎age ‎of 50 years. Although the ‎prevalence of PEG and advanced glaucoma increased with age, it ‎was ‎neither statistically associated with it, nor with sex‏.‏‎ Cataract prevalence ‎was associated ‎with increased age and male sex.‎

Management of Glaucoma Capsulare: Outcomes and Complications of Trabeculectomy

“…Association of pseudo-exfoliation to increased IOP has been well documented and proposed that patients with bilateral pseudo-exfoliation, are usually older and have higher prevalence of glaucoma or ocular hypertension in comparison to patients with unilateral involvement. 14,15 Genetic factors are also linked as a predisposing factor, however the results are still not clear and studies are still on-going in this respect. 16 In our study, patients had either unilateral or bilateral disease.…”