Clinical Science Population Distribution of Human Salivary Amylases: Differential Inhibition by Wheat Protein

Abstract

Based upon response to an inhibitor from wheat gliadin, 80 random samples of human salivary amylase were separated into three phenotypic groups. Each phenotype occurred with a high frequency rendering this a polymorphinc locus. The susceptibility to the inhibitor may be a useful marker for studies of tendency to caries and periodontal disease as well as for studies of genetic variation and linkage.

Review article Present‐day studies on cereals protein nature alpha‐amylase inhibitors

“…Human salivary amylases were shown to exhibit differing susceptibilities to the amylase inhibitor protein from wheat gliadin [79]. However, PACE et al…”