2016
DOI: 10.1186/s12933-016-0384-7
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Clinical relevance of dual-energy X-ray absorptiometry (DXA) as a simultaneous evaluation of fatty liver disease and atherosclerosis in patients with type 2 diabetes

Abstract: BackgroundWhole body dual-energy X-ray absorptiometry (DXA) can simultaneously measure both regional fat and non-fat mass. Android-to-gynoid (A/G) ratio measured by DXA has been reported to be associated with cardiovascular risks and visceral adiposity; however, little is known regarding its relationship with fatty liver disease and atherosclerosis among patients with diabetes. This study was designed to investigate the association of android and gynoid fat mass measured by DXA with fatty liver disease and ath… Show more

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Cited by 27 publications
(33 citation statements)
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“…We converted glycated hemoglobin values estimated by the Japan Diabetes Society method to the National Glycohemoglobin Standardization Program values. Sarcopenia (reduction of muscle mass and muscle strength) was determined by the criteria for Asians, using height, fat‐free mass in the upper and lower extremities measured by whole‐body dual‐energy X‐ray absorptiometry (Lunar iDXA; GE Healthcare, Madison, Wisconsin, USA) and the average of bilateral grasp power, as reported previously. Regarding the abdominal adiposity, visceral fat area (VFA) and subcutaneous fat area were measured by abdominal computed tomography as described previously.…”
Section: Methodsmentioning
confidence: 99%
“…We converted glycated hemoglobin values estimated by the Japan Diabetes Society method to the National Glycohemoglobin Standardization Program values. Sarcopenia (reduction of muscle mass and muscle strength) was determined by the criteria for Asians, using height, fat‐free mass in the upper and lower extremities measured by whole‐body dual‐energy X‐ray absorptiometry (Lunar iDXA; GE Healthcare, Madison, Wisconsin, USA) and the average of bilateral grasp power, as reported previously. Regarding the abdominal adiposity, visceral fat area (VFA) and subcutaneous fat area were measured by abdominal computed tomography as described previously.…”
Section: Methodsmentioning
confidence: 99%
“…The measurement was taken with each hand in a standing position, and the average of grip strength was used for muscle strength in this study. Regional fat and fat‐free mass were measured by the whole body DXA (Lunar iDXA, GE Healthcare, Madison, WI) as described previously . The appendicular skeletal muscle index (SMI) was calculated as the appendicular lean mass divided by the square of the height (kg/m 2 ).…”
Section: Methodsmentioning
confidence: 99%
“…Visceral fat area (VFA) and subcutaneous fat area (SFA) were measured at the level of umbilicus by abdominal CT examination (Aquilion PRIME, Toshiba Medical Systems, Tochigi, Japan) as described previously [15]. Hepatic fat accumulation was also determined by liver attenuation index (LAI) in the CT examination as described previously [16].…”
Section: Quantification Of Abdominal Adiposity Hepatic Fat Accumulatmentioning
confidence: 99%
“…Madison, WI) as described previously [15]. Skeletal muscle index (SMI) was calculated as the following: SMI = (appendicular non-fat mass, kg) divided by height (m) 2 .…”
Section: Efficacy and Safetymentioning
confidence: 99%