Clinical profile of neurological complications in HIV-reactive patients and their relation with CD4

Dhadke, Shubhangi V; Dhadke, Vithal Narayan; Mahajan, Neetin P; Korade, M B

doi:10.14194/ijmbr.3.2.5

Cited by 9 publications

(16 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Our results are comparable to Sinder et al [4] , Dhadje et al [7] , Patel et al [6] millogo et al [5] and patill et al [8] . snider et al in their study of 50 cases found that the age range was 25 to 56 years in HIV reactive patients with neurological manifestations.…”

Section: Methodssupporting

confidence: 90%

“…In our study 4 (7%) out of 57 patients with neurological manifestations had bacterial meningitis. This study was in accordance with Dhadke SV et al who observed 14 % [7] Satyendra et al 16.27%, [12] Sharma et al 5%, [10] Bolokadze et al 4% cases of bacterial meningitis. [17]…”

Section: Bacterial Meningitissupporting

confidence: 91%

“…Our study is comparable to a study done by Dhadke et al which showed that 76% patient had CD4 count <200/mm3 whereas only 24% patient had CD4 count >200/mm3, [7] Hemant et al studied HIV patients with neurological complication had other opportunistic infections and most of these patients had CD4 count less than 200, Only 10 (20%) of patients had CD4 counts more than 200. [13] Satyendra et al in a study of 38 HIV-infected patients with neurological manifestations observed that the mean CD4 count was 177.9 +105.0, of which 24 (63.2%) patients had CD4 count less than 200, [12] Sharma et al who did a study in 37 patients reported that in 13 (35.14%) patients CD4 count was between 200-500mm3.…”

Section: Cd4 Countsupporting

confidence: 89%

“…Cryptococcal meningitis based on CSF India ink preparation. Present study Sharma et al [10] Amit et al [23] Atili et al [9] Rana et al [11] Dhadke et al [7] Hemant et al…”

Section: Cryptococcal Meningitismentioning

confidence: 78%

“…[15] in a study by Teja et al, an overall prevalence of 25.6% was obtained, which ranged from 15.8% in 1993 to 26.6% in 2003. [16] [7] Rana et al [11] Patel et al [6] Satyendra et al [12] Sharma et al [10] Levy et al [20] Wadia et al [15] Tubercular meningitis Table 9: TBM Comparison Present study n=27 Hemant et al [13] Dhadke et al [7] Atili et al [9] Fever…”

Section: Neurological Manifestation Prevalence Of Neurological Manifementioning

confidence: 99%

See 4 more Smart Citations

Clinical Profile of Neurological Manifestations in HIVReactive Patients and Their Relation with CD4 Count

Sk¹,

Khurana²,

Kathuria³

et al. 2016

AIMDR

View full text Add to dashboard Cite

Background: Neurologic abnormalities have been noted in one-third of patients with AIDS, but at autopsy the nervous system is affected in all of them. Aim: To study the clinical profile of neurological manifestations in HIV reactive patients and their correlation with CD4 counts. Methods: A randomized case study was conducted at Department of Medicine, Government Medical College, Patiala over a period of 2 years. 200 HIV-infected adult and adolescent patients (>15 years of age) were studied. The diagnosis of HIV was confirmed by 3 HIV ELISA& RAPID positive reports in symptomatic patients. Results: In the present study, 37% of the patients were in the age group of 26-35 years. Males are affected more frequently than females, with a male to female sex ratio of 2.56: 1. Meningitis, HIV associated dementia, Progressive multifocal leukoencephalopathy& peripheral neuropathy are the commonest neurological disorders observed in HIV-infected patients. Tuberculosis is the commonest opportunistic infection in retroviral positive patients. Conclusion: Central nervous system infections, intracranial mass lesions, stroke, and HIV-associated dementia are more common in patients with a CD4+ count less than 200.

show abstract

Section: Methodssupporting

confidence: 90%

Section: Bacterial Meningitissupporting

confidence: 91%

Section: Cd4 Countsupporting

confidence: 89%

“…Cryptococcal meningitis based on CSF India ink preparation. Present study Sharma et al [10] Amit et al [23] Atili et al [9] Rana et al [11] Dhadke et al [7] Hemant et al…”

Section: Cryptococcal Meningitismentioning

confidence: 78%

Section: Neurological Manifestation Prevalence Of Neurological Manifementioning

confidence: 99%

See 3 more Smart Citations

Clinical Profile of Neurological Manifestations in HIVReactive Patients and Their Relation with CD4 Count

Sk¹,

Khurana²,

Kathuria³

et al. 2016

AIMDR

View full text Add to dashboard Cite

show abstract

Outcome of Guilian Barre'-Syndrome Using Clinical and Electrophysiological Parameters

Daoud,

Saeed,

Ahmed

et al. 2023

Preprint

View full text Add to dashboard Cite

Introduction: Guillian Barre'-Syndrome (GBS) is an acute, immune mediated disorder, commonly characterized by a rapidly progressive, ascending weakness of the extremity, trunk, respiratory and facial musculature, with inconstant sensory and autonomic dysfunction. This research conducted in Sudanese patients to study the relation between the outcome in GBS and a four parameters; age of the patient, onset duration, presence of autonomic dysfunction and the electrophysiological subtypes. Methods: A cross-sectional study involving the main three neurology centers in Sudan conducted from March to September 2020, 62 patients enrolled in the study, structured questionnaire consisted of personal data, clinical history, examination findings, management and outcome. The Hughes Functional Grading Scale (HFGS), which provides an objective measure of disability, was used to rate clinical performance at disease nadir and at 90 day from the illness. Results: The study revealed that males and females are equally represented, the majority of patients (70%) are between 18 and 50 years. The onset of weakness was less than or equal 3 days in (33.9%) of patients, from 4 to 7 days in (41.9%), from 8 to 14 days in (11.3%) and above 14 days in (12.9%).A 25 patients (40.3%) had Evidence of autonomic dysfunction. Based on the electrophysiology, (37.09%) of patients were classified as acute motor axonal neuropathy (AMAN), (29.03%) as acute inflammatory demyelinating poly neuropathy (AIDP) and (29.03%) as acute motor-sensory axonal neuropathy (AMSAN). Regarding the outcome, 30 patients (48.4%) fully recovered, 25 patients (40.3%) recovered with motor deficit, and 7 patients (11.3%) unfortunately died. The results showed that there was no statistically significance between different age groups, duration of onset or presence of autonomic dysfunction and the outcome after three months, P value ( .21, .21, .1) respectively. The results showed that the Prognosis after three months and the mortality rate of AMAN and AMSAN subtypes were poorer than that of AIDP. Conclusion: Axonal type of GBS found to be in nearly 2/3 patients. 40% showed clinical evidence of dysautonomia, and showed no statistical evidence with outcome, Age of the patients, onset of the disease also did not show statistically significant effect on outcome at day- 90. The outcome of axonal types at day-90 was poorer than that of demyelinating form.

show abstract

Tubercular Spinal Paravertebral Abscesses Presenting as Multiple Dermal Sinuses in HIV Reactive Patients

Sachdeva¹,

Khurana²,

Kathuria³

et al. 2016

AIMDR

View full text Add to dashboard Cite

Extra Pulmonary tuberculosis (EPTB) accounts for more than 50% of the cases of Tuberculosis in HIV-reactive patients and the clinically presentation is often atypical. EPTB sometimes poses diagnostic dilemmas as conventional diagnostic methods have a poor diagnostic yield and definite diagnosis may be delayed. Here we report a case of Spinal TB who uncommonly presented with multiple non healing sinuses in the Thoracolumbar region. Diagnosis was clinched by clinical presentation, +ve Interferon Gamma Release Assay (IGRA) accompanied by suggestive Magnetic resonance imaging findings.

show abstract

Clinical profile of neurological complications in HIV-reactive patients and their relation with CD4

Cited by 9 publications

References 10 publications

Clinical Profile of Neurological Manifestations in HIVReactive Patients and Their Relation with CD4 Count

Clinical Profile of Neurological Manifestations in HIVReactive Patients and Their Relation with CD4 Count

Outcome of Guilian Barre'-Syndrome Using Clinical and Electrophysiological Parameters

Tubercular Spinal Paravertebral Abscesses Presenting as Multiple Dermal Sinuses in HIV Reactive Patients

Contact Info

Product

Resources

About