Clinical profile of endometrial histopathological patterns in Abnormal Uterine Bleeding

Abstract

<jats:p>Aims: To study the association of clinical profile of patients with Abnormal Uterine Bleeding with the different endometrial histopathological patterns&#x0D; Methods: A retrospective cross-sectional study was done in the department of Obstetrics and Gynaecology at a hospital in Karnataka, India from January 2017 to January 2019. Medical records were reviewed for all the cases of abnormal uterine bleeding who underwent endometrial biopsy.&#x0D; Results: There were 148 records of endometrial biopsies; &gt;55% were in 41-50 years age group; 28% had postmenopausal bleeding; and 28% presented with menorrhagia. Menorrhagia and menometrorrhagia were equally common under 50 years of age. The various physiological patterns of endometrium (proliferative, secretory &amp; menstruating endometrium) were noted in more than half the cases (51%). Proliferative endometrium was in 37%, followed by hyperplasia without atypia in 22% and only 3% showed malignancy; all of whom were in the postmenopausal group. Even in women with post menopausal bleeding, proliferative pattern was the commonest (33%), followed by atrophic endometrium and malignancy. Atypical hyperplasia was found to be most commonly associated with post menopausal bleeding.&#x0D; Conclusions: Both physiological and non physiological endometrial patterns were seen almost equally among the AUB cases. The knowledge of endometrial pattern in a case of AUB helps to decide a plan of management. Endometrial sampling plays a very important role in management of AUB, especially in the age group of more than 40 yrs; i.e, the peri and post-menopausal age groups, where incidence of malignant or pre malignant conditions was noted to be the highest.&#x0D; Key words: abnormal uterine bleeding, endometrial cancer, endometrial sampling, hyperplasia</jats:p>

Study of histopathological patterns of endometrium in abnormal uterine bleeding

“…An earlier stage of presentation due to increase health awareness could explain high incidence in our study. 20 The incidence of endometrial hyperplasia in this study (5.11%) was less as compared to other studies as these patients may have been identified at a much earlier stage that is in the disordered proliferative phase. 19 Endometrial hyperplasia is a precursor of endometrial cancer.…”

To study the socio-demographic profile and clinical profile of abnormal uterine bleeding cases attending new civil hospital, Surat, Western India

“…Additionally, parity wise distribution in this study noted multipara patients in three-fourths (75%), followed by primiparas (16%) and nulliparas (9%). Similarly, most of the patients were multipara in Choudhary and Nath 7 study (89%) and Singh et al 6 study (71.7%) and Chauhan et al 8 The present study delves into the varied complaints reported by patients, with menorrhagia being the most prevalent (80%), followed by polymenorrhagia (18%) and metrorrhagia (2%). Moreover, heavy bleeding was reported in 75% of cases and extremely heavy bleeding in 25%.…”

Histopathological spectrum in cases of abnormal uterine bleeding: a cross sectional study in tertiary care hospital in Tripura

“…[17][18][19][20] The commonest myometrial lesion observed in present study were leiomyoma and majority of patients were in the range from 41-50 years age group (56.86%) which is in concordance with other studies done by Praseeda et al and Sapna et al where 33.5% and 55.0% respectively. 21,22 There are many minor factors or causes present AUB in the present study also but these are small number. These findings are in accordance to the many previous literature.…”